{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T22:24:00Z","timestamp":1782771840251,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T00:00:00Z","timestamp":1414972800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"crossref","award":["R37AG17560"],"award-info":[{"award-number":["R37AG17560"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Yale Claude D. Pepper Older Americans Independence Center","award":["P30AG21342"],"award-info":[{"award-number":["P30AG21342"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the relationship between back pain severe enough to restrict activity (restricting back pain) and subsequent mobility disability in community\u2010living older persons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Greater New Haven, Connecticut.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Community\u2010living men and women aged 70 and older (n\u00a0=\u00a0709).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Restricting back pain and mobility disability (defined as needing help with or unable to walk one\u2010quarter of a mile, climb a flight of stairs, or lift and carry 10 pounds) were assessed during monthly telephone interviews for up to 159\u00a0months. The association between restricting back pain and subsequent mobility disability was evaluated using a recurrent\u2010events Cox model. Secondary analyses evaluated the association between restricting back pain and mobility disability for two or more consecutive months (persistent mobility disability). Additional analyses were repeated in participants without baseline mobility disability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The event rate for mobility disability was 7.26 per 100\u2010person months (95% confidence interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      )\u00a0=\u00a06.89\u20137.64). Mobility disability episodes lasted for a median of 2\u00a0months (interquartile range (\n                      <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                      ) 1\u20134). In a recurrent\u2010event Cox regression analysis, after adjusting for 11 covariates, restricting back pain was strongly associated with mobility disability (hazard ratio (\n                      <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                      )\u00a0=\u00a03.23, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a02.87\u20133.64). The association was maintained when the outcome was defined as persistent mobility disability (adjusted\n                      <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                      \u00a0=\u00a03.63, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a03.15\u20134.20) and when participants with baseline mobility disability were omitted (adjusted\n                      <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                      \u00a0=\u00a03.71, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a03.22\u20134.28).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Restricting back pain was strongly associated with mobility disability. Interventions that prevent or ameliorate restricting back pain may be effective for reducing the burden of mobility disability in older persons.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.13089","type":"journal-article","created":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T11:33:55Z","timestamp":1415014435000},"page":"2142-2147","source":"Crossref","is-referenced-by-count":37,"title":["Restricting Back Pain and Subsequent Mobility Disability in Community\u2010Living Older Persons"],"prefix":"10.1111","volume":"62","author":[{"given":"Una E.","family":"Makris","sequence":"first","affiliation":[{"name":"Department of Medicine UT Southwestern Medical Center Dallas Texas"},{"name":"Department of Internal Medicine Veterans Administration Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liana","family":"Fraenkel","sequence":"additional","affiliation":[{"name":"Department of Medicine School of Medicine Yale University New Haven Connecticut"},{"name":"Department of Internal Medicine Veterans Administration Medical Center West Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Medicine School of Medicine Yale University New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Leo\u2010Summers","sequence":"additional","affiliation":[{"name":"Department of Medicine School of Medicine Yale University New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Gill","sequence":"additional","affiliation":[{"name":"Department of Medicine School of Medicine Yale University New Haven 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