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The\n                      <jats:styled-content style=\"fixed-case\">LDCW<\/jats:styled-content>\n                      , an endurance walking test (400\u00a0m), was administered at Years 1 (baseline), 2, 4, 6, and 8 to assess aerobic fitness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At baseline,\n                      <jats:styled-content style=\"fixed-case\">LDCW<\/jats:styled-content>\n                      completion times (adjusted for age and sex) were 351.8\u00a0seconds (95% confidence interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      )\u00a0=\u00a0346.9\u2013356.8\u00a0seconds) for the inactive group, 335.9\u00a0seconds (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a0332.7\u2013339.1\u00a0seconds) for the lifestyle active group, and 307.7\u00a0seconds (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a0303.2\u2013312.3\u00a0seconds) for the exerciser group (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). From baseline to Year 8, the inactive group slowed 36.1\u00a0seconds (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a028.4\u201343.8\u00a0seconds), the lifestyle active group slowed 38.1\u00a0seconds (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a033.6\u201342.4\u00a0seconds), and the exerciser group slowed 40.8\u00a0seconds (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a035.2\u201346.5\u00a0seconds), and did not differ significantly between groups. In linear mixed\u2010effects models, the rate of change in\n                      <jats:styled-content style=\"fixed-case\">LDCW<\/jats:styled-content>\n                      time did not differ between the groups, although exercisers consistently had the fastest completion times (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001 for all pairwise comparisons).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Decline in\n                      <jats:styled-content style=\"fixed-case\">LDCW<\/jats:styled-content>\n                      time occurred regardless of baseline activity, although exercisers maintained higher aerobic fitness, which may delay reaching a critically low threshold of aerobic fitness at which independence is impaired.\n                    <\/jats:p>\n                 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