{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T13:18:46Z","timestamp":1793884726210,"version":"4.7.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Suomen Akatemia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Finnish Ministry of Education"},{"name":"Juho Vainio Foundation"},{"name":"Medical Research Fund of Tampere University Hospital"},{"name":"National Doctoral Program of Musculoskeletal Disorders and Biomaterials (TBDP)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the effects of multimodal supervised exercise on physical functioning, falls, and related injuries in older women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Two\u2010year randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tampere, Finland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Women aged 70 to 80 who had fallen in the previous year (n\u00a0=\u00a0409).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>\n                      Participants were randomly assigned to an exercise or control group (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.Clinicaltrial.gov\">ClinicalTrial.gov<\/jats:ext-link>\n                      NCT00986466). Exercisers participated in group exercise classes twice a week for 12\u00a0months and once a week for the subsequent 12\u00a0months and home exercises. Controls maintained their current physical activity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Physical functioning assessed at baseline and at 6\u2010month intervals during the intervention. Falls and related injuries monitored with fall diaries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Intention\u2010to\u2010treat analyses showed that exercise led to significant improvements in physical functioning. Leg strength differed significantly between the groups (mean change: 14.1%, 95% confidence interval (CI)\u00a0=\u00a08.0 to 20.2 in exercisers; 1.6%, 95% CI\u00a0=\u00a0\u22124.5 to 7.7 in controls;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). Chair stand time also differed significantly between groups (7.4%, 95% CI 3.8 to 10.8% in exercisers; 2.4%, 95% CI\u00a0=\u00a0\u22121.6 to 6.2) in controls;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.02). Between\u2010group differences were significant for fast walking speed (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.003) and probability of completing the backward walking test (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001), favoring exercisers. Timed Up\u2010and\u2010Go and grip strength did not differ between groups. There was no difference in the total falls incidence rate ratio (IRR\u00a0=\u00a01.0, 95% CI\u00a0=\u00a00.79 to 1.26), but exercisers were less likely to have medically attended injurious falls (IRR\u00a0=\u00a00.45, 95% CI\u00a0=\u00a00.27 to 0.78;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.004).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Twenty\u2010four months of multimodal exercise enhanced physical functioning in women aged 70 to 80 with a history of falls. Although the total number of falls was not lower than in controls, the rate of medically attended injurious falls was more than 50% lower.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.13489","type":"journal-article","created":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T06:38:23Z","timestamp":1435300703000},"page":"1306-1313","source":"Crossref","is-referenced-by-count":46,"title":["Effects of a Multimodal Exercise Program on Physical Function, Falls, and Injuries in Older Women: A 2\u2010Year Community\u2010Based, Randomized Controlled Trial"],"prefix":"10.1111","volume":"63","author":[{"given":"Radhika","family":"Patil","sequence":"first","affiliation":[{"name":"UKK Institute for Health Promotion Research Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsti","family":"Uusi\u2010Rasi","sequence":"additional","affiliation":[{"name":"UKK Institute for Health Promotion Research Tampere Finland"},{"name":"Research Department 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