{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:10:01Z","timestamp":1789737001306,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T00:00:00Z","timestamp":1453161600000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["2013\u2013062881"],"award-info":[{"award-number":["2013\u2013062881"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the association between periodontitis and cognitive impairment in elderly Koreans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross\u2010sectional study with age\u2010 and sex\u2010matched case\u2013control selection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>\n                      The Yangpyeong cardiovascular cohort (\n                      <jats:styled-content style=\"fixed-case\">YCC<\/jats:styled-content>\n                      ), a part of the Korean Genome Epidemiologic Study (Ko\n                      <jats:styled-content style=\"fixed-case\">GES<\/jats:styled-content>\n                      ), Yangpyeong, South Korea.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      Individuals with cognitive impairment (n\u00a0=\u00a065) and cognitively normal controls (n\u00a0=\u00a0124) aged 60 and older from the\n                      <jats:styled-content style=\"fixed-case\">YCC<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Alveolar bone loss was assessed on dental panoramic radiographs to categorize the cumulative history of periodontitis (\n                      <jats:styled-content style=\"fixed-case\">HOP<\/jats:styled-content>\n                      ) into three groups: normal, moderate periodontitis, severe periodontitis. The Mini\u2010Mental State Examination (\n                      <jats:styled-content style=\"fixed-case\">MMSE<\/jats:styled-content>\n                      ) was used to categorize participants as cognitively normal or cognitively impaired. Age\u2010 and sex\u2010matched conditional logistic regression models were used for analysis. Confounders considered in the analysis were age, sex, drinking, smoking, exercise, total cholesterol, total protein, body mass index, fasting plasma glucose, intima\u2010media thickness, hypertension medication, and depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Participants with\n                      <jats:styled-content style=\"fixed-case\">HOP<\/jats:styled-content>\n                      were more likely to have cognitive impairment than those without (odds ratio\u00a0=\u00a02.14, 95% confidence interval\u00a0=\u00a01.04\u20134.41). The interaction effect of smoking and exercise on periodontitis highlighted the link.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Periodontitis was independently associated with cognitive impairment after controlling for various confounders. Further longitudinal research is needed to determine whether periodontitis plays a role in cognitive decline in older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.13781","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T04:22:30Z","timestamp":1453177350000},"page":"162-167","source":"Crossref","is-referenced-by-count":38,"title":["Periodontitis Is Associated with Cognitive Impairment in Elderly Koreans: Results from the Yangpyeong Cohort Study"],"prefix":"10.1111","volume":"64","author":[{"given":"Hye\u2010Sun","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Preventive and Social Dentistry Seoul National University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung\u2010Seop","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Dentistry Seoul National University Seoul 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