{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:16:40Z","timestamp":1784809000731,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T00:00:00Z","timestamp":1453161600000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG032052\u201303"],"award-info":[{"award-number":["R01 AG032052\u201303"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["1K24HD070966\u201301"],"award-info":[{"award-number":["1K24HD070966\u201301"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["1 UL1 RR025758\u201301"],"award-info":[{"award-number":["1 UL1 RR025758\u201301"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007299","name":"Harvard Catalyst","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007299","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To examine the effect of pain and mild cognitive impairment (\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      )\u2014together and separately\u2014on performance\u2010based and self\u2010reported mobility outcomes in older adults in primary care with mild to moderate self\u2010reported mobility limitations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross\u2010sectional analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Academic community outpatient clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Individuals aged 65 and older in primary care enrolled in the Boston Rehabilitative Impairment Study in the Elderly who were at risk of mobility decline (N\u00a0=\u00a0430).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Participants with an average score greater than three on the Brief Pain Inventory (\n                      <jats:styled-content style=\"fixed-case\">BPI<\/jats:styled-content>\n                      ) were defined as having pain.\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      was defined using age\u2010adjusted scores on a neuropsychological battery. Multivariable linear regression models assessed associations between pain and\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      , together and separately, and mobility performance (habitual gait speed, Short Physical Performance Battery), and self\u2010reports of function and disability in various day\u2010to\u2010day activities (Late Life Function and Disability Instrument).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The prevalence of pain was 34% and of\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      was 42%; 17% had pain only, 25% had\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      only, 17% had pain and\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      , and 41% had neither. Participants with pain and\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      performed significantly worse than all others on all mobility outcomes (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). Participants with\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      only or pain only also performed significantly worse on all mobility outcomes than those with neither (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Mild to moderate pain and\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      were independently associated with poor mobility, and the presence of both comorbidities was associated with the poorest status. Primary care practitioners who encounter older adults in need of mobility rehabilitation should consider screening them for pain and\n                      <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\n                      to better inform subsequent therapeutic interventions.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.13869","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T04:22:30Z","timestamp":1453177350000},"page":"138-143","source":"Crossref","is-referenced-by-count":40,"title":["Effect of Pain and Mild Cognitive Impairment on Mobility"],"prefix":"10.1111","volume":"64","author":[{"given":"Caroline A.","family":"Schepker","sequence":"first","affiliation":[{"name":"Spaulding Rehabilitation Hospital Boston Massachusetts"},{"name":"Department of Physical Medicine and Rehabilitation Harvard Medical School Boston Massachusetts"},{"name":"Touro University California College of Osteopathic Medicine Vallejo California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne G.","family":"Leveille","sequence":"additional","affiliation":[{"name":"Department of Nursing University of Massachusetts Boston Boston Massachusetts"},{"name":"Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette M.","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Spaulding Rehabilitation Hospital Boston Massachusetts"},{"name":"Clinical Research Centre Copenhagen University Hospital Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel E.","family":"Ward","sequence":"additional","affiliation":[{"name":"Spaulding Rehabilitation Hospital Boston Massachusetts"},{"name":"Department of Physical Medicine and Rehabilitation Harvard Medical School Boston Massachusetts"},{"name":"School of Public Health Boston University Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura A.","family":"Kurlinski","sequence":"additional","affiliation":[{"name":"Spaulding Rehabilitation Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Grande","sequence":"additional","affiliation":[{"name":"Psychology Service VA Boston Healthcare System Boston Massachusetts"},{"name":"Department of Psychiatry School of Medicine Boston University Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan K.","family":"Kiely","sequence":"additional","affiliation":[{"name":"Spaulding Rehabilitation Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan F.","family":"Bean","sequence":"additional","affiliation":[{"name":"Spaulding Rehabilitation Hospital Boston Massachusetts"},{"name":"Department of Physical Medicine and Rehabilitation Harvard Medical School Boston Massachusetts"},{"name":"New England Geriatric Research Education and Clinical Center VA Boston Healthcare System Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.07.029"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2011.05.013"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12848"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1738"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20100372"},{"key":"e_1_2_6_7_1","volume-title":"Older Americans 2010: Key Indicators of Well\u2010being","author":"Federal Interagency Forum on Aging Related Statistics","year":"2010"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu063"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2006.00091.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/49.2.M85"},{"key":"e_1_2_6_12_1","first-page":"391","volume-title":"Advances in Pain Research and Therapy","author":"Cleeland C","year":"1989"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2003.12.005"},{"key":"e_1_2_6_14_1","first-page":"129","article-title":"Pain assessment: Global use of the Brief Pain Inventory","volume":"23","author":"Cleeland C","year":"1994","journal-title":"Ann Acad Med"},{"key":"e_1_2_6_15_1","volume-title":"Neuropsychological Assessment","author":"Lezak MD","year":"2004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.390"},{"key":"e_1_2_6_17_1","volume-title":"Wechsler Adult Intelligence Scale, Third Ed. 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