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American Geriatrics Society"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To investigate the effects of a high\u2010intensity functional exercise program on independence in activities of\u00a0\u00a0daily living (\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      s) and balance in older people with dementia and whether exercise effects differed between dementia types.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cluster\u2010randomized controlled trial: Ume\u00e5 Dementia and Exercise (UMDEX) study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Residential care facilities, Ume\u00e5, Sweden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      Individuals aged 65 and older with a dementia diagnosis, a Mini\u2010Mental State Examination score of 10 or greater, and dependence in\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      s (N\u00a0=\u00a0186).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>Ninety\u2010three participants each were allocated to the high\u2010intensity functional exercise program, comprising lower limb strength and balance exercises, and 93 to a seated control activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Blinded assessors measured\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      independence using the Functional Independence Measure (\n                      <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content>\n                      ) and Barthel Index (\n                      <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>\n                      ) and balance using the Berg Balance Scale (\n                      <jats:styled-content style=\"fixed-case\">BBS<\/jats:styled-content>\n                      ) at baseline and 4 (directly after intervention completion) and 7\u00a0months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Linear mixed models showed no between\u2010group effect on\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      independence at 4 (\n                      <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content>\n                      =1.3, 95% confidence interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      )=\u22121.6\u20134.3;\n                      <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>\n                      =0.6, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      =\u22120.2\u20131.4) or 7 (\n                      <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content>\n                      =0.8, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      =\u22122.2\u20133.8;\n                      <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>\n                      =0.6, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      =\u22120.3\u20131.4) months. A significant between\u2010group effect on balance favoring exercise was observed at 4\u00a0months (\n                      <jats:styled-content style=\"fixed-case\">BBS<\/jats:styled-content>\n                      =4.2, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      =1.8\u20136.6). In interaction analyses, exercise effects differed\u00a0significantly between dementia types. Positive between\u2010group exercise effects were found in participants with non\u2010Alzheimer's dementia according to the\n                      <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content>\n                      at 7\u00a0months and\n                      <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">BBS<\/jats:styled-content>\n                      at 4 and 7\u00a0months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      In older people with mild to moderate dementia living in residential care facilities, a 4\u2010month high\u2010intensity functional exercise program appears to slow decline in\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      independence and improve balance, albeit only in participants with non\u2010Alzheimer's dementia.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.13880","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T04:22:30Z","timestamp":1453177350000},"page":"55-64","source":"Crossref","is-referenced-by-count":137,"title":["Effects of a High\u2010Intensity Functional Exercise Program on Dependence in Activities of Daily Living and Balance in Older Adults with Dementia"],"prefix":"10.1111","volume":"64","author":[{"given":"Annika","family":"Toots","sequence":"first","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Physiotherapy Ume\u00e5 University Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5kan","family":"Littbrand","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Physiotherapy Ume\u00e5 University Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Lindel\u00f6f","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Physiotherapy Ume\u00e5 University Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Wiklund","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Physiotherapy Ume\u00e5 University Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Holmberg","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Department of Public Health and Clinical Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Nordstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillemor","family":"Lundin\u2010Olsson","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Physiotherapy Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yngve","family":"Gustafson","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Rosendahl","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Rehabilitation Physiotherapy Ume\u00e5 University Ume\u00e5 Sweden"},{"name":"Department of Community Medicine and Rehabilitation Geriatric Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,19]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"World Health Organization.Dementia: A Public Health Priority[on\u2010line]. 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