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Depression was defined as a score of 16 or greater on the Center for Epidemiologic Studies Depression Scale.\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      was defined as according to self\u2010reported history or taking insulin or oral hypoglycemic medication.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Participants with depression and\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      declined an average of 6.5 points on the\n                      <jats:styled-content style=\"fixed-case\">MMSE<\/jats:styled-content>\n                      ; depression only, 4.4 points;\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      only, 7.8 points; and neither condition, 4.2 points across the six examination waves. Participants with\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      declined an average of 0.18 more points on the\n                      <jats:styled-content style=\"fixed-case\">MMSE<\/jats:styled-content>\n                      per year (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.001) than those with neither\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      nor depression, and those with comorbid\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      and depression declined 0.25 more points per year (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.002). Depression was associated with significantly greater cognitive decline (\n                      <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/jgs13883-math-0001.png\" xlink:title=\"urn:x-wiley:00028614:media:jgs13883:jgs13883-math-0001\"\/>\n                      \u00a0=\u00a0\u22120.11,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.05) after excluding participants with baseline cognitive impairment (\n                      <jats:styled-content style=\"fixed-case\">MMSE<\/jats:styled-content>\n                      score \u226417). Participants with\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      were 1.08 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a01.03\u20131.12) times as likely as those with neither\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      nor depression, and those with comorbid\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      and depression were 1.08 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u00a0=\u00a01.01\u20131.15) times as likely as those with neither\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      nor depression to develop severe cognitive impairment per year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      and comorbid depression and\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      are risk factors for cognitive decline in older Mexican Americans. Interventions that reduce the prevalence of depression and\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      in Mexican Americans may decrease the number of older adults who experience cognitive decline.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.13883","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T04:22:30Z","timestamp":1453177350000},"page":"109-117","source":"Crossref","is-referenced-by-count":24,"title":["Effects of Comorbid Depression and Diabetes Mellitus on Cognitive Decline in Older Mexican Americans"],"prefix":"10.1111","volume":"64","author":[{"given":"Brian","family":"Downer","sequence":"first","affiliation":[{"name":"Sealy Center on Aging University of Texas Medical Branch Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin N.","family":"Vickers","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Community Health University of Texas Medical Branch Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soham","family":"Al Snih","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences University of Texas Medical Branch Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukaila","family":"Raji","sequence":"additional","affiliation":[{"name":"Division of Geriatrics Department of Internal Medicine University of Texas Medical Branch Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriakos S.","family":"Markides","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Community Health University of Texas Medical Branch Galveston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-006-0159-x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-200107000-00015"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1370\/afm.1501"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.2136"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1068"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.10.2822"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.11.2668"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3233\/JAD-2011-101614","article-title":"Depression history, depressive symptoms, and incident dementia: The 3C Study","volume":"26","author":"Lenoir H","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2010.228"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.51.4.1256"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318227b227"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.63.2.161"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e31816029ec"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.4.598"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0891988707303604"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(03)00077-5"},{"key":"e_1_2_7_18_1","unstructured":"LangaKM KabetoM WeirD.Report on Race and Cognitive Impairment\u00a0Using HRS. 2010 Alzheimer's Disease Facts and Figures [on\u2010line] 2009.\u00a0Available athttp:\/\/www.alz.org\/documents_custom\/report_alzfactsfigures2010.pdfAccessed September 9 2014."},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2012-121420"},{"key":"e_1_2_7_20_1","unstructured":"Table\u00a09: Resident Population by Race Hispanic Origin and Age: 2000 and 2009. 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