{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:08:17Z","timestamp":1770746897633,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T00:00:00Z","timestamp":1461974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2016,5]]},"abstract":"\n Objectives<\/jats:title>\n \n To assess the serum of 25\u2010hydroxyvitamin D (25(\n OH<\/jats:styled-content>\n )D) and intact parathyroid hormone (\n iPTH<\/jats:styled-content>\n ) levels in postmenopausal women from northern China with hip and upper limb fractures.\n <\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Case\u2013control.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Affiliated Hospital of Qingdao University.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n Postmenopausal women diagnosed with hip fracture (n = 335) and matched controls without fracture (n = 335).<\/jats:p>\n <\/jats:sec>\n \n Measurements<\/jats:title>\n \n Between 2011 and 2013, fasting venous samples were analyzed for 25(\n OH<\/jats:styled-content>\n )D,\n iPTH<\/jats:styled-content>\n , alkaline phosphatase (\n ALP<\/jats:styled-content>\n ), calcium, and phosphorus. All women completed a standardized questionnaire designed to document putative risk factors for fractures.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Eight percent of participants had vitamin D deficiency, and 66.0% had secondary hyperparathyroidism. Serum 25(\n OH<\/jats:styled-content>\n )D levels were significantly (\n P<\/jats:italic>\n < .001) lower in women with hip fracture than in controls. Multivariate logistic regression analysis adjusted for common risk factors showed that serum 25(\n OH<\/jats:styled-content>\n )D of 20 ng\/mL or less was an independent indicator of hip fracture (odds ratio (\n OR<\/jats:styled-content>\n ) = 2.98, 95% confidence interval (\n CI<\/jats:styled-content>\n ) = 2.11\u20134.20) and concomitant upper limb fracture in those with existing hip fractures (\n OR<\/jats:styled-content>\n = 4.77, 95%\n CI<\/jats:styled-content>\n = 1.60\u201310.12). The area under the receiver operating characteristic curve of 25(\n OH<\/jats:styled-content>\n )D was 0.77 (95%\n CI<\/jats:styled-content>\n = 0.68\u20130.84) for hip fracture and 0.80 (95%\n CI<\/jats:styled-content>\n = 0.72\u20130.89) for hip and upper limb fractures.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Vitamin D insufficiency and secondary hyperparathyroidism were a common problem in postmenopausal women who presented with concomitant hip and upper limb fractures, suggesting that they might contribute to the pathophysiology of fractures in postmenopausal women.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jgs.14082","type":"journal-article","created":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T07:31:29Z","timestamp":1462087889000},"page":"1068-1072","source":"Crossref","is-referenced-by-count":7,"title":["Serum of 25\u2010Hydroxyvitamin D and Intact Parathyroid Hormone Levels in Postmenopausal Women with Hip and Upper Limb Fractures"],"prefix":"10.1111","volume":"64","author":[{"given":"Jiang\u2010Tao","family":"Lv","sequence":"first","affiliation":[{"name":"Department of Orthopedics Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying\u2010Ying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao\u2010Qi","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Affiliated Hospital of Qingdao University Qingdao 266003 Shandong Province 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