{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T21:16:22Z","timestamp":1770326182208,"version":"3.49.0"},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,4,23]],"date-time":"2016-04-23T00:00:00Z","timestamp":1461369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005036","name":"Universitetet i Bergen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005036","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine how development of delirium after surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) could predict activity of daily living (ADL) and instrumental ADLs (IADL) disability, cognitive function, and self\u2010reported health in individuals aged 80 and older.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary university hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Individuals aged 80 and older undergoing elective SAVR or TAVI (N = 136).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Delirium was assessed for 5 days using the Confusion Assessment Method. The Barthel Index, Nottingham Extended ADL Scale, and SF\u201012 were used to determine ADL and IADL ability and self\u2010reported health at baseline and 1\u2010 and 6\u2010month follow\u2010up. Cognition was assessed using the Mini\u2010Mental State Examination at baseline and 6\u2010month follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Participants had lower IADL scores 1 month after SAVR than at baseline (baseline 58, 1 month: delirium 42, no delirium 50,\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 .02), but scores had returned to baseline levels at 6 months. The Medical Outcomes Study 12\u2010item Short\u2010Form Health Survey (SF\u201012) Physical Component Summary (PCS) score was higher at 6\u2010month follow\u2010up (48) than at baseline (39), especially in participants who did not develop delirium (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001). No differences in other outcomes were found. Regression models suggest that delirium may help predict IADL disability 1 month after baseline (\n                      <jats:italic>P<\/jats:italic>\n                      \u2264 .07) but does not predict large differences in ADL disability, cognitive function, or SF\u201012\u2010scores. Individuals who underwent TAVI and developed delirium had lower ADL (baseline 19, 1\u2010month 16,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001) and IADL (baseline 49, 1\u2010month 40,\n                      <jats:italic>P<\/jats:italic>\n                      = .003) scores at 1\u2010month follow\u2010up. SF\u201012 PCS score (baseline 30) increased from baseline to 1\u2010 (35,\n                      <jats:italic>P<\/jats:italic>\n                      = .04) and 6\u2010 (35,\n                      <jats:italic>P<\/jats:italic>\n                      = .02) month follow\u2010up in individuals who underwent TAVI and did not develop delirium. Delirium after TAVI predicted greater ADL and IADL disability at 1\u2010month but not at 6\u2010month follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Individuals who develop delirium after SAVR and TAVI have poorer short\u2010term IADL function but do not seem to have long\u2010term reductions in physical, mental, or self\u2010reported health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.14165","type":"journal-article","created":{"date-parts":[[2016,4,23]],"date-time":"2016-04-23T04:29:27Z","timestamp":1461385767000},"page":"1178-1186","source":"Crossref","is-referenced-by-count":28,"title":["Delirium as a Predictor of Physical and Cognitive Function in Individuals Aged 80 and Older After Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement"],"prefix":"10.1111","volume":"64","author":[{"given":"Leslie S. P.","family":"Eide","sequence":"first","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette H.","family":"Ranhoff","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Kavli Research Center for Geriatrics and Dementia Haraldsplass Hospital Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bengt","family":"Fridlund","sequence":"additional","affiliation":[{"name":"School of Health and Welfare J\u00f6nk\u00f6ping University J\u00f6nk\u00f6ping Sweden"},{"name":"Department of Heart Disease Haukeland University Hospital Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rune","family":"Haaverstad","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Heart Disease Haukeland University Hospital Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3170-9496","authenticated-orcid":false,"given":"Karl Ove","family":"Hufthammer","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research Haukeland University Hospital Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karel K. J.","family":"Kuiper","sequence":"additional","affiliation":[{"name":"Department of Heart Disease Haukeland University Hospital Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan E.","family":"Nordrehaug","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Cardiology Stavanger University Hospital Stavanger Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tone M.","family":"Norekv\u00e5l","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Heart Disease Haukeland University Hospital Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Delirium in Octogenarians Undergoing Cardiac Surgery or Intervention\u2013CARDELIR Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.795260"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.02013.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezr031"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.015"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69208-8"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1202277"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2013.10.006"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.02762.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182147f6d"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.07.006"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.12.043"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.02.014"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182949a2e"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.11.010"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs173"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs455"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-12-941"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01674.x"},{"key":"e_1_2_6_21_1","first-page":"61","article-title":"Functional evaluation: The Barthel Index","volume":"14","author":"Mahoney FI","year":"1965","journal-title":"Md State Med J"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/jscd.2001.24656"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/22.6.419"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/09638289209166426"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12635"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(02)00799-6"},{"key":"e_1_2_6_30_1","unstructured":"European System for Cardiac Operative Risk Evaluation[on\u2010line]. 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