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Adjusting for\n WMH<\/jats:styled-content>\n did not change associations.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n In young, middle\u2010aged, and older adults with prevalent cardiovascular risk factors, multiple inflammatory biomarkers were associated with slower walking speed independent of microvascular disease in the brain. There was little evidence of mediation by brain\n WMH<\/jats:styled-content>\n volume. Inflammation may contribute to physical function impairments through pathways other than brain microvascular disease, particularly in\n AA<\/jats:styled-content>\n s.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jgs.14229","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T13:33:43Z","timestamp":1466084023000},"page":"1448-1455","source":"Crossref","is-referenced-by-count":21,"title":["Associations Between Inflammation and Physical Function in African Americans and European Americans with Prevalent Cardiovascular Risk Factors"],"prefix":"10.1111","volume":"64","author":[{"given":"B. 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