{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:08:04Z","timestamp":1785881284592,"version":"3.56.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T00:00:00Z","timestamp":1466035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science, and Technology","doi-asserted-by":"publisher","award":["24390156"],"award-info":[{"award-number":["24390156"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H\u201025\u2010Chojyu\u2010007"],"award-info":[{"award-number":["H\u201025\u2010Chojyu\u2010007"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To examine the association between four markers of overall nutritional status (a serum biomarker (albumin) and three anthropometric indices (body mass index (\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      ), midarm circumference (\n                      <jats:styled-content style=\"fixed-case\">MAC<\/jats:styled-content>\n                      ), calf circumference (\n                      <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content>\n                      ))) and incident hearing impairment in older Japanese adults.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Community\u2010based prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Kurabuchi Town, Gunma Prefecture, Japan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Individuals aged 65 and older (143 men, 195 women) without hearing impairment at baseline examination (2005\u201306) who participated in repeated examinations 4 years later (2009\u201310) (N = 338).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      The three anthropometric indices were measured at baseline, and nephelometry was used to assess serum albumin levels. Hearing impairment was defined as failure to hear a 30\u2010\n                      <jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content>\n                      hearing level signal at 1\n                      <jats:styled-content style=\"fixed-case\">kH<\/jats:styled-content>\n                      z and a 40\u2010\n                      <jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content>\n                      signal at 4\n                      <jats:styled-content style=\"fixed-case\">kH<\/jats:styled-content>\n                      z in the better ear on pure\u2010tone audiometry.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Over the 4\u2010year period, 16.3% of participants developed hearing impairment. Those with lower marker values had greater risk of hearing impairment than those with higher marker values (multivariable adjusted odds ratio (\n                      <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                      ) = 2.18, 95% confidence interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ) = 1.05\u20134.57 for albumin \u22644.0 g\/\n                      <jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>\n                      ;\n                      <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                      = 2.72, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 1.10\u20136.71 for\n                      <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\n                      &lt;19.0 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). The pattern of association showed a similar tendency for\n                      <jats:styled-content style=\"fixed-case\">MAC<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content>\n                      . Excluding obese participants did not changed the results substantially.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Further research is needed to determine whether interventions that improve markers of nutritional status may help prevent age\u2010related hearing loss in older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.14245","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T13:33:09Z","timestamp":1466083989000},"page":"1480-1485","source":"Crossref","is-referenced-by-count":13,"title":["Markers of Overall Nutritional Status and Incident Hearing Impairment in Community\u2010Dwelling Older Japanese: The Kurabuchi Study"],"prefix":"10.1111","volume":"64","author":[{"given":"Takehiro","family":"Michikawa","sequence":"first","affiliation":[{"name":"Environmental Epidemiology Section Centre for Environmental Health Sciences National Institute for Environmental Studies Tsukuba Japan"},{"name":"Department of Preventive Medicine and Public Health School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health School of Medicine Toho University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Imamura","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health School of Medicine Toho University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunio","family":"Mizutari","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery National Defense Medical College Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Takebayashi","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Nishiwaki","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health School of Medicine Toho University Tokyo 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