{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:23:09Z","timestamp":1790029389075,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T00:00:00Z","timestamp":1477526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG030141"],"award-info":[{"award-number":["R01AG030141"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["AGK24AG022345"],"award-info":[{"award-number":["AGK24AG022345"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["5P30AG028741"],"award-info":[{"award-number":["5P30AG028741"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K23AG031218"],"award-info":[{"award-number":["K23AG031218"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compared outcomes of regional nerve blocks with those of standard analgesics after hip fracture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Multisite randomized controlled trial from April 2009 to March 2013.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Three New York hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Individuals with hip fracture (N = 161).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>\n                      Participants were randomized to receive an ultrasound\u2010guided, single\u2010injection, femoral nerve block administered by emergency physicians at emergency department (\n                      <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>\n                      ) admission followed by placement of a continuous fascia iliaca block by anesthesiologists within 24 hours (n = 79) or conventional analgesics (n = 82).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Pain (0\u201310 scale), distance walked on Postoperative Day (\n                      <jats:styled-content style=\"fixed-case\">POD<\/jats:styled-content>\n                      ) 3, walking ability 6 weeks after discharge, opioid side effects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Pain scores 2 hours after\n                      <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>\n                      presentation favored the intervention group over controls (3.5 vs 5.3,\n                      <jats:italic>P<\/jats:italic>\n                      = .002). Pain scores on\n                      <jats:styled-content style=\"fixed-case\">POD<\/jats:styled-content>\n                      3 were significantly better for the intervention than the control group for pain at rest (2.9 vs 3.8,\n                      <jats:italic>P<\/jats:italic>\n                      = .005), with transfers out of bed (4.7 vs 5.9,\n                      <jats:italic>P<\/jats:italic>\n                      = .005), and with walking (4.1 vs 4.8,\n                      <jats:italic>P<\/jats:italic>\n                      = .002). Intervention participants walked significantly further than controls in 2 minutes on\n                      <jats:styled-content style=\"fixed-case\">POD<\/jats:styled-content>\n                      3 (170.6 feet, 95% confidence interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ) = 109.3\u2013232 vs 100.0 feet, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 65.1\u2013134.9;\n                      <jats:italic>P<\/jats:italic>\n                      = .04). At 6 weeks, intervention participants reported better walking and stair climbing ability (mean Functional Independence Measure locomotion score of 10.3 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 9.6\u201311.0) vs 9.1 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 8.2\u201310.0),\n                      <jats:italic>P<\/jats:italic>\n                      = .04). Intervention participants were significantly less likely to report opioid side effects (3% vs 12.4%,\n                      <jats:italic>P<\/jats:italic>\n                      = .03) and required 33% to 40% fewer parenteral morphine sulfate equivalents.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Femoral nerve blocks performed by emergency physicians followed by continuous fascia iliaca blocks placed by anesthesiologists are feasible and result in superior outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.14386","type":"journal-article","created":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T10:27:03Z","timestamp":1477564023000},"page":"2433-2439","source":"Crossref","is-referenced-by-count":150,"title":["Regional Nerve Blocks Improve Pain and Functional Outcomes in Hip Fracture: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"64","author":[{"given":"R. Sean","family":"Morrison","sequence":"first","affiliation":[{"name":"Department of Anesthesia Icahn School of Medicine at Mount Sinai New York City New York"},{"name":"Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York City New York"},{"name":"James J. Peters Veterans Affairs Medical Center Bronx New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eitan","family":"Dickman","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center Brooklyn New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ula","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York City New York"},{"name":"James J. 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