{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:46:29Z","timestamp":1783723589224,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K24AG050685"],"award-info":[{"award-number":["K24AG050685"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG032298"],"award-info":[{"award-number":["R01 AG032298"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG041780"],"award-info":[{"award-number":["R01 AG041780"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["5P30 AG024824"],"award-info":[{"award-number":["5P30 AG024824"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["F32 AI102552"],"award-info":[{"award-number":["F32 AI102552"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K99 DK105205"],"award-info":[{"award-number":["K99 DK105205"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To determine the relationship between clinically diagnosed catheter\u2010associated urinary tract infection (\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      ) and standardized criteria and to assess microorganism\u2010level differences in symptom burden in a cohort of catheterized nursing home (\n                      <jats:styled-content style=\"fixed-case\">NH<\/jats:styled-content>\n                      ) residents.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Post hoc analysis of a prospective longitudinal study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>\n                      Twelve\n                      <jats:styled-content style=\"fixed-case\">NH<\/jats:styled-content>\n                      s in southeast Michigan.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">NH<\/jats:styled-content>\n                      residents with indwelling urinary catheters (n = 233; 90% white, 52% male, mean age 73.7).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Clinical and demographic data, including\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      epidemiology and symptoms, were obtained at study enrollment, 14 days, and monthly thereafter for up to 1 year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred twenty participants with an indwelling catheter (51%) were prescribed systemic antibiotics for 182 clinically diagnosed\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      s. Common signs and symptoms were acute change in mental status (28%), fever (21%), and leukocytosis (13%). Forty percent of clinically diagnosed\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      s met Loeb's minimum criteria, 32% met National Health Safety Network (\n                      <jats:styled-content style=\"fixed-case\">NHSN<\/jats:styled-content>\n                      ) criteria, and 50% met Loeb's minimum or\n                      <jats:styled-content style=\"fixed-case\">NHSN<\/jats:styled-content>\n                      criteria.\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      s involving\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      and\n                      <jats:italic>Enterococcus<\/jats:italic>\n                      spp. were least likely to meet criteria.\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      s involving\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      were most likely to meet Loeb's minimum criteria (odds ratio (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      ) = 9.7, 95% confidence interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ) = 2.3\u201340.3), possibly because of an association with acute change in mental status (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      = 5.9, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      = 1.8\u201319.4).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Fifty percent of clinically diagnosed\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      s met standardized criteria, which represents an improvement in antibiotic prescribing practices. At the microorganism level, exploratory data indicate that symptom burden may differ between microorganisms. Exploration of\n                      <jats:styled-content style=\"fixed-case\">CAUTI<\/jats:styled-content>\n                      signs and symptoms associated with specific microorganisms may yield beneficial information to refine existing tools to guide appropriate antibiotic treatment.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.14533","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T11:54:32Z","timestamp":1479297272000},"page":"395-401","source":"Crossref","is-referenced-by-count":70,"title":["How Often Do Clinically Diagnosed Catheter\u2010Associated Urinary Tract Infections in Nursing Homes Meet Standardized Criteria?"],"prefix":"10.1111","volume":"65","author":[{"given":"Chelsie E.","family":"Armbruster","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology School of Medicine University of Michigan Ann Arbor 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