{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:48Z","timestamp":1787015568362,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T00:00:00Z","timestamp":1488758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA069533"],"award-info":[{"award-number":["P30 CA069533"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2017,7]]},"abstract":"\n Objectives<\/jats:title>\n \n To compare the prevalence of and association between falls and frailty of prostate cancer survivors (\n PCS<\/jats:styled-content>\n s) who were current, past or never users of androgen deprivation therapy (\n ADT<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Cross\u2010sectional.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Mail and electronic survey.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n \n PCS<\/jats:styled-content>\n s (N = 280; mean age 72 \u00b1 8).\n <\/jats:p>\n <\/jats:sec>\n \n Measurements<\/jats:title>\n Cancer history, falls, and frailty status (robust, prefrail, frail) using traditionally defined and obese phenotypes.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Current (37%) or past (34%)\n ADT<\/jats:styled-content>\n users were more than twice as likely to have fallen in the previous year as never users (15%) (\n P<\/jats:italic>\n = .002).\n ADT<\/jats:styled-content>\n users had twice as many recurrent falls (\n P<\/jats:italic>\n < .001) and more fall\u2010related injuries than unexposed men (\n P<\/jats:italic>\n = .01). Current (43%) or past (40%)\n ADT<\/jats:styled-content>\n users were more likely to be classified as prefrail or frail than never users (15%) (\n P<\/jats:italic>\n < .001), and the prevalence of combined obese frailty + prefrailty was even greater in current (59%) or past (62%)\n ADT<\/jats:styled-content>\n users than never users (25%) (\n P<\/jats:italic>\n < .001). Traditional and obese frailty significantly increased the likelihood of reporting falls in the previous year (odds ratio (\n OR<\/jats:styled-content>\n ) = 2.15, 95%\n CI<\/jats:styled-content>\n = 1.18\u20133.94 and\n OR<\/jats:styled-content>\n = 2.97, 95%\n CI<\/jats:styled-content>\n = 1.62\u20135.58, respectively) and was also associated with greater risk of recurrent falls (\n OR<\/jats:styled-content>\n = 3.10, 95%\n CI<\/jats:styled-content>\n = 1.48\u20136.5 and\n OR<\/jats:styled-content>\n = 3.99, 95%\n CI<\/jats:styled-content>\n = 1.79\u20138.89, respectively).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Current and past exposure to\n ADT<\/jats:styled-content>\n is linked to higher risk of falls and frailty than no treatment.\n PCS<\/jats:styled-content>\n s should be appropriately counseled on fall prevention strategies, and approaches to reduce frailty should be considered.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jgs.14795","type":"journal-article","created":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T10:32:48Z","timestamp":1488796368000},"page":"1414-1419","source":"Crossref","is-referenced-by-count":77,"title":["Falls and Frailty in Prostate Cancer Survivors: Current, Past, and Never Users of Androgen Deprivation Therapy"],"prefix":"10.1111","volume":"65","author":[{"given":"Kerri M.","family":"Winters\u2010Stone","sequence":"first","affiliation":[{"name":"Knight Cancer Institute Oregon Health & Science University Portland Oregon"},{"name":"School of Nursing Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Moe","sequence":"additional","affiliation":[{"name":"Department of Medicine Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie N.","family":"Graff","sequence":"additional","affiliation":[{"name":"Knight Cancer Institute Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan F.","family":"Dieckmann","sequence":"additional","affiliation":[{"name":"School of Nursing Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydnee","family":"Stoyles","sequence":"additional","affiliation":[{"name":"School of Nursing Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Borsch","sequence":"additional","affiliation":[{"name":"School of Nursing Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshi J.","family":"Alumkal","sequence":"additional","affiliation":[{"name":"Knight Cancer Institute Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L.","family":"Amling","sequence":"additional","affiliation":[{"name":"Knight Cancer Institute Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz M.","family":"Beer","sequence":"additional","affiliation":[{"name":"Knight Cancer Institute Oregon Health & Science University Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,6]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Cancer Facts & Figures 2015.Atlanta:American Cancer Society 2015."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2011.103"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.11.024"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1207506"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.64.9285"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00518-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2008.51"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1405095"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2013.06.008"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1385\/JCD:4:4:381"},{"key":"e_1_2_6_12_1","unstructured":"Centers for Disease Control and Prevention.Falls Among Older Adults: An Overview [on\u2010line]. 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