{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:09:30Z","timestamp":1790298570873,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T00:00:00Z","timestamp":1490745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AG007181\u201015"],"award-info":[{"award-number":["AG007181\u201015"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR06828"],"award-info":[{"award-number":["AR06828"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      Investigate associations of diffuse idiopathic skeletal hyperostosis (\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      ) with self\u2010reported and measured physical function in older adults.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross\u2010sectional analyses of data collected in 1992\u201396 from a longitudinal cohort. Setting: Research clinic within a community.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      Community\u2010dwelling men (n = 630) and women (n = 961), mean age 71.5 years (\n                      <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                      = 10.8), from the Rancho Bernardo Study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      assessed from lateral thoracic and lumbar spine radiographs; self\u2010reported difficulty bending over to the floor, walking 2\u20133 level blocks, or climbing 1 flight of stairs; performance\u2010based measures of grip strength and chair\u2010stand testing (ability to stand up and sit down in a chair 5 times without using chair arms).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      was present in 25.6% of men and 5.5% of women. In age and sex\u2010adjusted models, those with\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      had 1.72\u2010fold increased odds (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.13, 2.62) of self\u2010reported difficulty bending; this remained significant after further adjustment for Cobb angle, weight, stroke, arthritis, and exercise,\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      = 1.69, (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.07, 2.66). In fully adjusted multivariate models, those with\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      had worse grip strength, \u22121.08 kg,\n                      <jats:italic>P<\/jats:italic>\n                      = .01, but did not differ from those without\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      on walking or climbing stairs. In sex\u2010stratified, fully adjusted models, among men only, those with\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      were 2.17\u2010times (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.04, 4.52) more likely to be unable to complete 5 chair stands without using their arms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      was less prevalent in women but affected almost one\u2010quarter of older white men. People with\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      are more likely to experience physical functional impairment, suggesting that\n                      <jats:styled-content style=\"fixed-case\">DISH<\/jats:styled-content>\n                      has clinical correlations and is not an incidental radiographic finding.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.14810","type":"journal-article","created":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T14:26:07Z","timestamp":1490797567000},"page":"1476-1481","source":"Crossref","is-referenced-by-count":35,"title":["Diffuse Idiopathic Skeletal Hyperostosis (\n                    <scp>DISH<\/scp>\n                    ) and Impaired Physical Function: The Rancho Bernardo Study"],"prefix":"10.1111","volume":"65","author":[{"given":"Wendy B.","family":"Katzman","sequence":"first","affiliation":[{"name":"University of California San Francisco California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Hua","family":"Huang","sequence":"additional","affiliation":[{"name":"University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Kritz\u2010Silverstein","sequence":"additional","affiliation":[{"name":"University of California San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Barrett\u2010Connor","sequence":"additional","affiliation":[{"name":"University of California San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah M.","family":"Kado","sequence":"additional","affiliation":[{"name":"University of California San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-013-3154-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2011.01.001"},{"key":"e_1_2_6_4_1","article-title":"Cross\u2010sectional and longitudinal associations of diffuse idiopathic skeletal hyperostosis (DISH) and thoracic kyphosis in older men and women","author":"Katzman WB","year":"2016","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"e_1_2_6_5_1","first-page":"506","article-title":"Diffuse idiopathic skeletal hyperostosis: A distinct clinical entity","volume":"5","author":"Mader R","year":"2003","journal-title":"Isr Med Assoc 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