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We examined the association between protein intake and the onset of mobility limitation over 6 years of follow\u2010up in older adults in the Health\n                      <jats:styled-content style=\"fixed-case\">ABC<\/jats:styled-content>\n                      study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Memphis, Tennessee and Pittsburgh, Pennsylvania.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Community\u2010dwelling, initially well\u2010functioning adults aged 70\u201379 years (n = 1998).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Protein intake (g\/kg body weight\/d) was calculated using an interviewer\u2010administered 108\u2010item food frequency questionnaire at baseline. Mobility limitation was assessed semi\u2010annually and defined as reporting any difficulty walking one\u2010quarter of a mile or climbing 10 steps on 2 consecutive 6\u2010month contacts. The association between protein intake and incident mobility limitation was examined using Cox proportional hazard regression models adjusting for demographics, behavioral characteristics, chronic conditions, total energy intake, and height.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean (\n                      <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                      ) protein intake was 0.91 (0.38) g\/kg body weight\/d, with 43% reporting intakes less than the\n                      <jats:styled-content style=\"fixed-case\">RDA<\/jats:styled-content>\n                      (0.8 g\/kg body weight\/d). During 6 years of follow\u2010up, 705 participants (35.3%) developed mobility limitations. Compared to participants in the upper tertile of protein intake (\u22651.0 g\/kg body weight\/d), participants in the lower two tertiles of protein intake (&lt;0.7 and 0.7 \u2013&lt;1.0 g\/kg body weight\/d) were at greater risk of developing mobility limitation over 6 years of follow\u2010up (\n                      <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>\n                      (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ): 1.86 (1.41\u20132.44) and 1.49 (1.20\u20131.84), respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Lower protein intake was associated with increased risk of mobility limitation in community\u2010dwelling, initially well\u2010functioning older adults. These results suggest that protein intakes of \u22651.0 g\/kg body weight\/d may be optimal for maintaining physical function in older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.14856","type":"journal-article","created":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T11:38:17Z","timestamp":1489750697000},"page":"1705-1711","source":"Crossref","is-referenced-by-count":95,"title":["Protein Intake and Mobility Limitation in Community\u2010Dwelling Older Adults: the Health\n                    <scp>ABC<\/scp>\n                    Study"],"prefix":"10.1111","volume":"65","author":[{"given":"Denise K.","family":"Houston","sequence":"first","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet A.","family":"Tooze","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelyn","family":"Garcia","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein","family":"Visser","sequence":"additional","affiliation":[{"name":"Vrije Universiteit Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Rubin","sequence":"additional","affiliation":[{"name":"University of California San Francisco California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara B.","family":"Harris","sequence":"additional","affiliation":[{"name":"National Institute on Aging Bethesda Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne B.","family":"Newman","sequence":"additional","affiliation":[{"name":"University of Pittsburgh Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Kritchevsky","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Health ABC Study","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nutr.22.010402.102715"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00075197-200111000-00007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/61.10.1059"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51534.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.3.324"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.00540.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00246.2003"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/87.5.1562S"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2013.01.014"},{"key":"e_1_2_6_11_1","volume-title":"Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. 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