{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T11:38:18Z","timestamp":1762169898582,"version":"build-2065373602"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T00:00:00Z","timestamp":1507507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To determine whether potentially inappropriate medications (\n                      <jats:styled-content style=\"fixed-case\">PIM<\/jats:styled-content>\n                      s) or potentially inappropriate associations (\n                      <jats:styled-content style=\"fixed-case\">PIA<\/jats:styled-content>\n                      s) prescribed knowingly are associated with patient monitoring.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Geriatric units (n = 56) in 28 hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Inpatients aged 75 and older (N = 1,327).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Potentially inappropriate prescriptions (\n                      <jats:styled-content style=\"fixed-case\">PIP<\/jats:styled-content>\n                      ) were defined as a\n                      <jats:styled-content style=\"fixed-case\">PIM<\/jats:styled-content>\n                      or a\n                      <jats:styled-content style=\"fixed-case\">PIA<\/jats:styled-content>\n                      selected by an expert board from lists of explicit criteria (Beers, Priscus, Laroche, French Health Agency) using a Delphi process. They were considered to be prescribed knowingly if they were maintained after reassessment by the geriatrician and the clinical pharmacist. Primary outcome was the rate of\n                      <jats:styled-content style=\"fixed-case\">PIP<\/jats:styled-content>\n                      s maintained (prescribed knowingly) and for which a geriatrician declared that specific monitoring was performed. Secondary outcomes were the parameters monitored and the rate of participants receiving knowingly a\n                      <jats:styled-content style=\"fixed-case\">PIP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One thousand sixty\u2010three\n                      <jats:styled-content style=\"fixed-case\">PIP<\/jats:styled-content>\n                      s were detected in 607 participants (46%). After reassessment, 826 (78%)\n                      <jats:styled-content style=\"fixed-case\">PIP<\/jats:styled-content>\n                      s were maintained in 490 participants (37%), the main reasons being participant's regular treatment and lack of alternative. Psychotropic (36%), cardiovascular (including antithrombotics) (29%), and laxative or antiemetic drugs (16%) were the most\u2010frequent classes prescribed knowingly. The geriatricians declared to perform clinical or biological monitoring for 69% (n = 570) of\n                      <jats:styled-content style=\"fixed-case\">PIM<\/jats:styled-content>\n                      s or\n                      <jats:styled-content style=\"fixed-case\">PIA<\/jats:styled-content>\n                      s prescribed knowingly. Three types of specific monitoring were identified: clinical, biological, and follow\u2010up with a specialist.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Approximately three\u2010quarters of\n                      <jats:styled-content style=\"fixed-case\">PIM<\/jats:styled-content>\n                      s or\n                      <jats:styled-content style=\"fixed-case\">PIA<\/jats:styled-content>\n                      s were prescribed knowingly, of which 69% were monitored, with wide variations in occurrence and in quality according to drug classes. This underlines the need for accurate guidelines on\n                      <jats:styled-content style=\"fixed-case\">PIP<\/jats:styled-content>\n                      monitoring.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.15081","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T02:36:47Z","timestamp":1507516607000},"page":"2713-2719","source":"Crossref","is-referenced-by-count":14,"title":["Monitoring of Potentially Inappropriate Prescriptions in Older Inpatients: A French Multicenter Study"],"prefix":"10.1111","volume":"65","author":[{"given":"Ir\u00e8ne","family":"Pandraud\u2010Riguet","sequence":"first","affiliation":[{"name":"Service de Pharmacie H\u00f4pital Saint\u2010Antoine Assistance Publique \u2013 H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Bonnet\u2010Zamponi","sequence":"additional","affiliation":[{"name":"Observatoire 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