{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:56:50Z","timestamp":1789041410950,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T00:00:00Z","timestamp":1539388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG024826"],"award-info":[{"award-number":["P30 AG024826"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 AG024827"],"award-info":[{"award-number":["P30 AG024827"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>To evaluate the Pittsburgh Fatigability Scale (PFS) as a predictor of performance and functional decline in mobility\u2010intact older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DESIGN<\/jats:title>\n                    <jats:p>Longitudinal analysis of Baltimore Longitudinal Study of Aging data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SETTING<\/jats:title>\n                    <jats:p>National Institute on Aging, Clinical Research Unit, Baltimore, Maryland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PARTICIPANTS<\/jats:title>\n                    <jats:p>Mobility\u2010intact men (46.8%) and women aged 60 to 89 with concurrent PFS administration and performance and functional assessment and follow\u2010up assessment within 1 to 4 years (N=579).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MEASUREMENTS<\/jats:title>\n                    <jats:p>\n                      The PFS is a self\u2010administered, 1\u2010page assessment of expected physical and mental fatigue with a score ranging from 0 (no) to 5 (extreme) associated with performing 10 activities. Analyses examined associations between each dimension scored continuously (0\u201350), categorically (0\u20135), and dichotomously and change in and likelihood of clinically meaningful decline in usual and fast gait speed, chair stand pace, and reported walking ability. Covariates included age, age\n                      <jats:sup>2<\/jats:sup>\n                      , sex, race, visit status, baseline function, and follow\u2010up time. We defined meaningful decline as 0.05\u2009m\/s per year for usual gait speed, 0.07\u2009m\/s per year for fast gait speed, 0.02 chair stands\/s per year and 1 point or more for walking ability index.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Over a mean 2.2 years, 20.5% to 37.7% of participants experienced meaningful decline across assessments. Independent of covariates, higher PFS physical and mental scores were most consistently associated with greater decline in usual gait speed, chair stand pace, and reported walking ability regardless of scoring approach. For example, higher physical fatigability was associated with twice the likelihood of meaningful decline in gait speed as lower physical fatigability (p=.001). PFS scores were superior to fatigue symptoms such as tiredness and energy level in predicting performance decline, which showed no association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      Routine self\u2010administered perceived fatigability assessment may help identify older persons vulnerable to accelerated mobility decline.\n                      <jats:bold>J Am Geriatr Soc 66:2092\u20132096, 2018.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.15531","type":"journal-article","created":{"date-parts":[[2018,10,13]],"date-time":"2018-10-13T11:54:28Z","timestamp":1539431668000},"page":"2092-2096","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["Pittsburgh Fatigability Scale: One\u2010Page Predictor of Mobility Decline in Mobility\u2010Intact Older Adults"],"prefix":"10.1111","volume":"66","author":[{"given":"Eleanor M.","family":"Simonsick","sequence":"first","affiliation":[{"name":"Intramural Research Program National Institute on Aging  Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Schrack","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Bloomberg School of Public Health Johns Hopkins University  Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam J.","family":"Santanasto","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Graduate School of Public Health University of Pittsburgh  Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie A.","family":"Studenski","sequence":"additional","affiliation":[{"name":"Intramural Research Program National Institute on Aging  Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Ferrucci","sequence":"additional","affiliation":[{"name":"Intramural Research Program National Institute on Aging  Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy W.","family":"Glynn","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Graduate School of Public Health University of Pittsburgh  Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,13]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2010.03.022"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14138"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12638"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2012.04062.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glx181"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13191"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(94)00125-O"},{"key":"e_1_2_4_9_1","first-page":"677","article-title":"The revised Piper Fatigue Scale: Psychometric evaluation in women with breast cancer","volume":"24","author":"Piper BF","year":"1998","journal-title":"Oncology Nurs Forum"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(93)90104-N"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12122"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7489(98)00005-4"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-004-5680-0"},{"key":"e_1_2_4_14_1","unstructured":"CooperR PophamM SantanastoAJet al.Are BMI and inflammatory markers independently associated with physical fatigability in old age? 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