{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T02:12:53Z","timestamp":1781835173254,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T00:00:00Z","timestamp":1539302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To characterize the cardiovascular disease (CVD) profile of individuals aged 80 and older in rural South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>First wave of population\u2010based longitudinal cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Agincourt subdistrict (Mpumalanga Province) in rural South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Adults residents (N\u2009=\u20095,059).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>In\u2010person interviews were conducted to obtain social, behavioral, economic, and clinical data. Prevalence of hypertension, diabetes, dyslipidemia, high waist\u2010to\u2010hip ratio, overweight and obesity, high\u2010risk high\u2010sensitivity C\u2010reactive protein, smoking, stroke, myocardial infarction, angina pectoris, and heart failure in individuals younger than 65, aged 65 to 79, and aged 80 and older were compared. Associations between self\u2010reported treatments and determinants of hypertension treatment in those aged 80 and older were assessed using multivariable regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 5,059 individuals included, 549 (10.8%) were aged 80 and older, and their CVD prevalence was 17.9% (stroke 3.8%, myocardial infarction 0.5%, angina pectoris 13.5%, heart failure 0.7%). Hypertension prevalence in this group was 73.8%, and along with angina pectoris, it increased with age (p&lt;.001), whereas overweight and obesity (46.4%), dyslipidemia (39.1%), and smoking prevalences (3.1%) decreased (p&lt;.001). Hypertension treatment was significantly associated with being aged 80 and older (odds ratio (OR)=1.48; 95% confidence interval (CI)=1.14\u20131.92, p=.003). Male sex (OR=0.73, 95% CI=0.66\u20130.88, p=.001), being an immigrant (OR=0.80, 95% CI=0.65\u20130.98; p=.03), higher socioeconomic status (OR=1.28, 95% CI=1.06\u20131.53, p=.009), and higher depression score (OR=1.12, 95% CI=1.05\u20131.19, p&lt;.001) were associated with hypertension treatment in those aged 80 and older.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This is the first study to characterize the CVD profile of individuals aged 80 and older in sub\u2010Saharan Africa and provides baseline data for comparison with future studies in this rapidly growing age group.\n                      <jats:bold>J Am Geriatr Soc 66:2151\u20132157, 2018.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.15567","type":"journal-article","created":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T12:06:23Z","timestamp":1539345983000},"page":"2151-2157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cardiovascular Disease Profile of the Oldest Adults in Rural South Africa: Data from the HAALSI Study (Health and Aging in Africa: Longitudinal Studies of INDEPTH Communities)"],"prefix":"10.1111","volume":"66","author":[{"given":"Thiago Veiga","family":"Jardim","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Center for Health Decision Science, T.H. 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Chan School of Public Health Harvard University  Cambridge Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Tollman","sequence":"additional","affiliation":[{"name":"Medical Research Council"},{"name":"Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences University of the Witwatersrand  Johannesburg South Africa"},{"name":"Center for Population and Development Studies, T.H. Chan School of Public Health Harvard University  Cambridge Massachusetts"},{"name":"INDEPTH Network  Accra Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Berkman","sequence":"additional","affiliation":[{"name":"Center for Population and Development Studies, T.H. 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