{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:57:25Z","timestamp":1790391445865,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T00:00:00Z","timestamp":1538697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100002429","name":"Amgen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002429","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>To estimate the incremental direct medical care costs associated with first fracture observable in high\u2010risk older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DESIGN<\/jats:title>\n                    <jats:p>Retrospective analysis of claims and survey data over a 3\u2010year period from the Health and Retirement Study (HRS), a nationally representative biennial study of individuals aged 50 and older.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SETTING<\/jats:title>\n                    <jats:p>United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PARTICIPANTS<\/jats:title>\n                    <jats:p>Participants were HRS respondents who consented to have their Medicare claims data linked to the HRS data, were aged 65 or older, had at least 1 risk factor for fracture observable in the data, and experienced a fracture between 1996 and 2008 (n = 689) and their propensity score\u2013matched controls (n = 689).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MEASUREMENTS<\/jats:title>\n                    <jats:p>Total Medicare, inpatient, outpatient, emergency department, physician office visit, and prescription drug care expenditures were primary outcomes. Two\u2010staged generalized linear models were estimated using a difference\u2010in\u2010differences model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Fracture cases\u2019 total Medicare expenditures increased by $13,929 (95% confidence interval (CI)=$11,920\u201315,938, p &lt;.001) more than those of matched controls from the year before the index or fracture date to 1 year after the index date. Inpatient expenditures of $12,751 (95% CI=$10,790\u201314,7111, p &lt; .001) more for fracture cases than comparison cases primarily drove this increase. Two and 3 years after fracture, there were no significant differences in growth in expenditures between the two groups. Results did not vary according to whether the fracture was at the hip or other site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      Fractures impose a significant economic burden, especially in the first year after the fracture, in Medicare beneficiaries with at least 1 risk factor for fracture. Our sample was limited to community\u2010dwelling individuals, and we are unable to control for fracture history before the study period. Costs may be greater for those in skilled nursing and similar facilities and for those who have had a previous fracture.\n                      <jats:bold>J Am Geriatr Soc 66:2298\u20132304, 2018<\/jats:bold>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.15585","type":"journal-article","created":{"date-parts":[[2018,10,6]],"date-time":"2018-10-06T06:08:35Z","timestamp":1538806115000},"page":"2298-2304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Medical Costs for Osteoporosis\u2010Related Fractures in High\u2010Risk Medicare Beneficiaries"],"prefix":"10.1111","volume":"66","author":[{"given":"Kandice A.","family":"Kapinos","sequence":"first","affiliation":[{"name":"RAND Corporation  Arlington Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1124-4962","authenticated-orcid":false,"given":"Shira H.","family":"Fischer","sequence":"additional","affiliation":[{"name":"RAND Corporation  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Mulcahy","sequence":"additional","affiliation":[{"name":"RAND Corporation  Arlington Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orla","family":"Hayden","sequence":"additional","affiliation":[{"name":"RAND Corporation  Santa Monica California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Barron","sequence":"additional","affiliation":[{"name":"Amgen, Inc.  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