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with an understanding of the diagnostic implications of using SDOC variables and cut\u2010points in mobility\u2010limited older adults. Using data from older individuals with specific conditions that render them at increased risk for mobility limitation, we evaluated the performance characteristics (ie, sensitivity and specificity) of five putative sarcopenia parameters and then compared these values with previously recommended diagnostic criteria for sarcopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DESIGN<\/jats:title>\n                    <jats:p>Retrospective analysis of six randomized controlled trials enriched in persons at risk for mobility limitation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SETTING<\/jats:title>\n                    <jats:p>National and international geriatric clinical research centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PARTICIPANTS<\/jats:title>\n                    <jats:p>A total of 925 mobility\u2010limited older adults (\u226555\u2009years of age; 58% women) were included in the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MEASUREMENTS<\/jats:title>\n                    <jats:p>The prevalence of low muscle strength and lean mass were assessed using five candidate metrics discriminative of slowness. Analyses of sensitivity and specificity were used to compare muscle weakness criteria with published diagnostics for sarcopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Odds ratios (ORs) supported maximal grip strength (Grip max &lt;35.5 and 20.0 in men and women, respectively) as the most discriminative of slowness in both men and women (OR = 3.66 and 3.53, respectively). More men (58%) than women (30%) fell below sex\u2010specific maximal grip cut\u2010points. When applying previously recommended sarcopenia component definitions in our population, we found that fewer individuals met those criteria (range = 6%\u201032%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>A greater number of individuals fall below SDOC Grip max cut\u2010points compared with previous recommendations. Clinicians and researchers working with older adults may consider these thresholds as an inclusive means to identify candidates for low\u2010risk lifestyle promyogenic and function\u2010promoting therapies. J Am Geriatr Soc 68:1445\u20101453, 2020.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.16525","type":"journal-article","created":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T09:18:30Z","timestamp":1594113510000},"page":"1445-1453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Application of\n                    <scp>Cut\u2010Points<\/scp>\n                    for Low Muscle Strength and Lean Mass in\n                    <scp>Mobility\u2010Limited<\/scp>\n                    Older Adults"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8929-4903","authenticated-orcid":false,"given":"Gregory J.","family":"Grosicki","sequence":"first","affiliation":[{"name":"Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center Tufts University  Boston Massachusetts"},{"name":"Department of Health Sciences and Kinesiology, Biodynamics and Human Performance Center Georgia Southern University (Armstrong Campus)  Savannah Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Travison","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center Harvard Medical School  Boston Massachusetts"},{"name":"Marcus Institute for Aging Research Hebrew SeniorLife  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Marcus Institute for Aging Research Hebrew SeniorLife  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Magaziner","sequence":"additional","affiliation":[{"name":"School of Medicine University of Maryland  Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen F.","family":"Binder","sequence":"additional","affiliation":[{"name":"Division of Geriatrics &amp; Nutritional Science Washington University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Pahor","sequence":"additional","affiliation":[{"name":"Department of Aging and Geriatric Research University of Florida  Gainesville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosaly","family":"Correa\u2010de\u2010Araujo","sequence":"additional","affiliation":[{"name":"U.S. Department of Health and Human Services, Division of Geriatrics and Clinical Gerontology National Institute of Aging, National Institutes of Health  Bethesda Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4938-9478","authenticated-orcid":false,"given":"Peggy M.","family":"Cawthon","sequence":"additional","affiliation":[{"name":"San Francisco Coordinating Center California Pacific Medical Research Institute  San Francisco California"},{"name":"Department of Epidemiology and Biostatistics University of California  San Francisco California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalender","family":"Bhasin","sequence":"additional","affiliation":[{"name":"Research Program in Men\u02bcs Health: Aging and Metabolism, Boston Claude D. 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