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Total annualized direct healthcare costs and utilization were ascertained during 36\u2009months after the Y7 examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean total annualized costs (2020 U.S. dollars) steadily increased across category of life\u2010space score, from $7954 (standard deviation [SD] 16,576) among men with life\u2010space scores of 101\u2013120 to $26,430 (SD 28,433) among men with life\u2010space scores of 0\u201340 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). After adjustment for demographics, men with a life\u2010space score of 0\u201340 versus men with a life\u2010space score of 101\u2013120 had greater mean total costs (cost ratio [CR]\u00a0=\u00a02.52; 95% confidence interval [CI]\u00a0=\u00a01.84\u20133.45) and greater risk of subsequent hospitalization (odds ratio [OR] 4.72, 95% CI 2.61\u20138.53) and skilled nursing facility (SNF) stay (OR 7.32, 95% CI 3.65\u201314.66). Life\u2010space score was no longer significantly associated with total healthcare costs (CR for 0\u201340 vs 101\u2013120 1.29; 95% CI 0.91\u20131.84) and hospitalization (OR 1.76, 95% CI 0.89\u20133.51) after simultaneous consideration of demographics, medical factors, self\u2010reported health and function, and the frailty phenotype; the association of life\u2010space with SNF stay remained significant (OR 2.86, 95% CI 1.26\u20136.49).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our results highlight the importance of function and mobility in predicting future healthcare costs and suggest the simple and convenient life\u2010space score may in part capture risks from major geriatric domains and improve identification of older, community\u2010dwelling men likely to require costly care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.17187","type":"journal-article","created":{"date-parts":[[2021,5,8]],"date-time":"2021-05-08T23:36:25Z","timestamp":1620516985000},"page":"2262-2272","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["<scp>Life\u2010space<\/scp>\n                    mobility and healthcare costs and utilization in older men"],"prefix":"10.1111","volume":"69","author":[{"given":"Kerry M.","family":"Sheets","sequence":"first","affiliation":[{"name":"Department of Medicine Hennepin Healthcare  Minneapolis Minnesota USA"},{"name":"Center for Care Delivery &amp; 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