{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:13:00Z","timestamp":1790773980944,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T00:00:00Z","timestamp":1626998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["R01\u2010NR012459"],"award-info":[{"award-number":["R01\u2010NR012459"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["N01\u2010AG\u20106\u20102101"],"award-info":[{"award-number":["N01\u2010AG\u20106\u20102101"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["N01\u2010AG\u20106\u20102103"],"award-info":[{"award-number":["N01\u2010AG\u20106\u20102103"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["N01\u2010AG\u20106\u20102106"],"award-info":[{"award-number":["N01\u2010AG\u20106\u20102106"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01\u2010AG028050"],"award-info":[{"award-number":["R01\u2010AG028050"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["T32\u2010AG055381"],"award-info":[{"award-number":["T32\u2010AG055381"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The purpose was to examine whether longitudinal changes in self\u2010reported energy predict incident mobility disability and mortality. We further explored whether changes in energy\u2010related behaviors (physical activity, appetite, or sleep quality) would explain these associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a02021 participants from the Health, Aging and Body Composition Study free from mobility disability and with at least three energy assessments from years 2 to 10.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>The outcomes were time to first self\u2010reported inability to walk a quarter of a mile (mobility disability) and death. Self\u2010reported energy level (SEL) was a single\u2010item indicator over the prior month, ranging from 0 to 10; person\u2010specific slopes measured whether individuals increased or decreased in SEL across the total follow\u2010up time (mean 7.09\u2009years, +1.72, range 2\u20138\u2009years). Potential energy\u2010related mediators were baseline and change in self\u2010reported physical activity, appetite, and sleep quality. Covariates were baseline levels and change in demographics, health characteristics and behaviors, tiredness, cognition, mood, and gait speed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 947 developed disability and 567 died over the study follow\u2010up. A one\u2010point change in SEL over the follow\u2010up (or an average 0.125 points\/year) was inversely associated with a 35% risk of incident mobility disability (hazard ratio\u00a0=\u00a00.65, 95% confidence interval [CI]\u00a0=\u00a00.55, 0.76,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and 33% risk of death (hazard ratio\u00a0=\u00a00.67, 95% CI\u00a0=\u00a00.42, 0.87,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003), independent of covariates. Potential energy\u2010related mediators did not attenuate this association.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this longitudinal analysis of community\u2010dwelling older adults, energy decline was common and a significant independent predictor of disability risk and mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.17372","type":"journal-article","created":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T15:25:37Z","timestamp":1627053937000},"page":"3134-3141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Declining energy predicts incident mobility disability and mortality risk in healthy older adults"],"prefix":"10.1111","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9035-8855","authenticated-orcid":false,"given":"Briana N.","family":"Sprague","sequence":"first","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaonan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2810-6045","authenticated-orcid":false,"given":"Rebecca C.","family":"Ehrenkranz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2706-1439","authenticated-orcid":false,"given":"Qu","family":"Tian","sequence":"additional","affiliation":[{"name":"Longitudinal Studies Section, Translational Gerontology Branch National Institute on Aging  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa A.","family":"Gmelin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2265-0162","authenticated-orcid":false,"given":"Nancy W.","family":"Glynn","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea L.","family":"Rosso","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Rosano","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health, University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gerinurse.2017.08.002"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gerinurse.2007.07.002"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt089"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/63.7.707"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2018.02.014"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/21641846.2018.1558733"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-014-0839-9"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-021-01788-0"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glv150"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200636090-00004"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3182a036ab"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2015.00289"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2012.00082"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25797"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12149"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-6494.1997.tb00326.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.newideapsych.2019.100752"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-181140"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.04.033"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.10.m644"},{"issue":"8","key":"e_1_2_10_23_1","first-page":"314","article-title":"The modified mini\u2010mental state (3MS) examination","volume":"48","author":"Teng EL","year":"1987","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_10_24_1","volume-title":"Manual for the Wechsler Adult Intelligence Scale, Revised","author":"Wechsler D","year":"1981"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16577"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03324782"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/geroni\/igaa061"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/21641846.2019.1573790"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0827-7"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.08.031"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.17372","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgs.17372","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.17372","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:32:22Z","timestamp":1762187542000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.17372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,23]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/jgs.17372"],"URL":"https:\/\/doi.org\/10.1111\/jgs.17372","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,23]]},"assertion":[{"value":"2020-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}