{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T08:41:48Z","timestamp":1767084108425,"version":"build-2065373602"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Video capsule endoscopy (VCE) is an effective, noninvasive modality for small bowel (SB) investigation. Its usage in the older adults is rising. However, data in octa\u2010nonagenarians regarding diagnostic yield and motility are lacking. Our aim was to evaluate and compare safety and efficacy of VCE between age subgroups of older adult patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective study of prospectively documented data. All consecutive VCEs of patients \u226565\u2009years (01\/2010\u201312\/2017) were included. Patients unable to swallow the capsule or videos with significant recording technical malfunction were excluded. The cohort was divided into the younger group aged 65\u201379\u2009years old and octa\u2010nonagenarians aged \u226580\u2009years old. Indications for referral, diagnostic yield and transit times were compared between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 535 VCEs were performed in 499 older adult patients (51.2% males); 82.8% were 65\u201379\u2009years old and 17.2% were\u2009\u226580\u2009years old. The \u226580\u2010year\u2010old group had higher rates of clinically significant findings (52.7% vs. 40.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.025), active bleeding (12.5% vs. 6.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.053) and angioectasia (36.0% vs. 23.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.014). Crohn's disease was newly diagnosed in approximately 8% of the entire cohort and 12% of the \u226580\u2009years old. Anemia was the most common indication in both groups, followed by overt bleeding in the \u226580\u2010year\u2010old group (25% vs. 9.9% in 65\u201379\u2010year\u2010old group,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u20090.001) and Crohn's disease in the 65\u201379\u2009years old (17.2% vs. 5.4% in \u226580\u2009years old,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.004). Groups were comparable in transit time and cecal documentation rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In octa\u2010nonagenarians, VCE is as safe as in younger older\u2010adults with a higher diagnostic yield of significant and treatable conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.17953","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T10:19:05Z","timestamp":1657016345000},"page":"2958-2966","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Octa\u2010nonagenarians can perform video capsule endoscopy safely and with a higher diagnostic yield than 65\u201379\u2010year\u2010old patients"],"prefix":"10.1111","volume":"70","author":[{"given":"Tamar","family":"Thurm","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Liver Diseases Tel\u2010Aviv Sourasky Medical Center  Tel\u2010Aviv Israel"},{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Gluck","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Liver Diseases Tel\u2010Aviv Sourasky Medical Center  Tel\u2010Aviv Israel"},{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orly","family":"Barak","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"},{"name":"Geriatric Division Tel\u2010Aviv Sourasky Medical Center  Tel\u2010Aviv 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