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We examined AF symptom perception, its impact on quality of life (QoL), and its relation to treatment strategies in older adults with AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were obtained from older adults with AF enrolled in a multicenter study conducted at clinic sites in Massachusetts and Georgia between 2016 and 2018. Participants were stratified into three age groups: 65\u201374 (youngest\u2013old), 75\u201384 (middle\u2013old), and \u226585 (oldest). Perception of AF symptoms was assessed by participant self\u2010report during their clinic visit and at study enrollment by the Atrial Fibrillation Effect on Quality\u2010of\u2010Life Questionnaire which assessed cardiac\u2010specific and non\u2010specific, non\u2010cardiac AF symptoms and their impact on QoL. Treatment strategies (rate or rhythm control) utilized were ascertained from electronic medical records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 1184 participants (mean age 75\u2009years, 48% women, 86% Non\u2010Hispanic White), 51% were aged 65\u201374\u2009years, 36% were 75\u201384\u2009years, and 13% were\u2009\u2265\u200985\u2009years. The most commonly reported AF symptoms were non\u2010specific, non\u2010cardiac symptoms (fatigue, dyspnea, lightheadedness) with similar prevalence and impact on QoL in all age groups. Cardiac\u2010specific AF symptoms (palpitations, irregular heartbeat, pause in heart activity) were less prevalent, but most commonly reported by the youngest participants (65\u201374\u2009years), who endorsed considerable impact of these symptoms on their QoL. Overall, those who reported experiencing any AF symptoms during their clinic visit were more likely to have received rhythm compared with rate control (OR: 1.56; 95% CI: 1.18\u20132.04) with similar findings for all age groups except those aged \u226585\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings suggest a high prevalence of non\u2010specific, non\u2010cardiac symptoms among older adults with AF and that cardiac\u2010specific AF symptoms may exert considerable impact on their QoL. The presence of any AF symptoms may drive more rhythm control in a majority of older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.17954","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T04:38:35Z","timestamp":1657082315000},"page":"2805-2817","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Perception of atrial fibrillation symptoms: Impact on quality of life and treatment in older adults"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9359-7373","authenticated-orcid":false,"given":"Hawa O.","family":"Abu","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"},{"name":"Department of Internal Medicine Saint Vincent Hospital  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9435-0145","authenticated-orcid":false,"given":"Weijia","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith M.","family":"Otabil","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane S.","family":"Saczynski","sequence":"additional","affiliation":[{"name":"Department of Pharmacy and Health Systems Sciences School of Pharmacy, Northeastern University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordy","family":"Mehawej","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Saint Vincent Hospital  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayra","family":"Tisminetzky","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine and Meyers Health Care Institute. Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"},{"name":"Department of Population and Quantitative Health Sciences University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Blanchard","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Internal Medicine Saint Vincent Hospital  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry H.","family":"Gurwitz","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine and Meyers Health Care Institute. Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"},{"name":"Department of Population and Quantitative Health Sciences University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"McManus","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine University of Massachusetts Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005119"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00583-9"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.8.983"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.821306"},{"key":"e_1_2_11_6_1","unstructured":"National Center for Chronic Disease Prevention and Health Promotion Division for Heart Disease and Stroke Prevention.https:\/\/www.cdc.gov\/dhdsp\/data_statistics\/fact_sheets\/fs_atrial_fibrillation.htm Accessed November 29 2020."},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2018.05.011"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.069450"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2016.11.008"},{"issue":"4","key":"e_1_2_11_10_1","first-page":"136","article-title":"Quality of life, exercise capacity and comorbidity in old patients with permanent atrial fibrillation","volume":"1","author":"Ariansena I","year":"2008","journal-title":"J Atr Fibrillation"},{"issue":"5","key":"e_1_2_11_11_1","first-page":"1169","article-title":"Significance and management strategies for patients with asymptomatic atrial fibrillation","volume":"7","author":"Majos E","year":"2015","journal-title":"J Atr Fibrillation"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.004498"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcaa040"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016651"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16178"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.060061"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010017\u20100621\u20102"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_2_11_21_1","unstructured":"BjornerJB S\u00f8ndergaard KristensenT Orth\u2010Gom\u00e9rK TibblinG SullivanM WesterholmP.Self\u2010Rated Health: A Useful Concept in Research Prevention and Clinical Medicine. 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