{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T18:39:29Z","timestamp":1782239969037,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T00:00:00Z","timestamp":1659744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5U01AG048270"],"award-info":[{"award-number":["5U01AG048270"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KL2TR000113"],"award-info":[{"award-number":["KL2TR000113"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30AG031679"],"award-info":[{"award-number":["P30AG031679"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30AG021342"],"award-info":[{"award-number":["P30AG021342"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30AG024824"],"award-info":[{"award-number":["P30AG024824"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30AG024827"],"award-info":[{"award-number":["P30AG024827"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30AG024832"],"award-info":[{"award-number":["P30AG024832"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR000114"],"award-info":[{"award-number":["UL1TR000114"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR000142"],"award-info":[{"award-number":["UL1TR000142"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Falls are common in older adults and can lead to severe injuries. The Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial cluster\u2010randomized 86 primary care practices across 10 health systems to a multifactorial intervention to prevent fall injuries, delivered by registered nurses trained as falls care managers, or enhanced usual care. STRIDE enrolled 5451 community\u2010dwelling older adults age \u226570 at increased fall injury risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We assessed fall\u2010related outcomes via telephone interviews of participants (or proxies) every 4 months. At baseline, 12 and 24\u2009months, we assessed health\u2010related quality of life (HRQOL) using the EQ\u20105D\u20105L and EQ\u2010VAS. We used Poisson models to assess intervention effects on falls, fall\u2010related fractures, fall injuries leading to hospital admission, and fall injuries leading to medical attention. We used hierarchical longitudinal linear models to assess HRQOL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      For recurrent event models, intervention versus control incidence rate ratios were 0.97 (95% confidence interval [CI], 0.93\u20131.00;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.048) for falls, 0.93 (95% CI, 0.80\u20131.08;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.337) for self\u2010reported fractures, 0.89 (95% CI, 0.73\u20131.07;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.205) for adjudicated fractures, 0.91 (95% CI, 0.77\u20131.07;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.263) for falls leading to hospital admission, and 0.97 (95% CI, 0.89\u20131.06;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.477) for falls leading to medical attention. Similar effect sizes (non\u2010significant) were obtained for dichotomous outcomes (e.g., participants with \u22651 events). The difference in least square mean change over time in EQ\u20105D\u20105L (intervention minus control) was 0.009 (95% CI, \u22120.002 to 0.019;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.106) at 12\u2009months and 0.005 (95% CI, \u22120.006 to 0.015;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.384) at 24\u2009months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Across a standard set of outcomes typically reported in fall prevention studies, we observed modest improvements, one of which was statistically significant. Future work should focus on patient\u2010, practice\u2010, and organization\u2010level operational strategies to increase the real\u2010world effectiveness of interventions, and improving the ability to detect small but potentially meaningful clinical effects.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">Clinicaltrials.gov<\/jats:ext-link>\n                      identifier: NCT02475850.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.17964","type":"journal-article","created":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T10:06:15Z","timestamp":1659780375000},"page":"3221-3229","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Effect of the\n                    <scp>STRIDE<\/scp>\n                    fall injury prevention intervention on falls, fall injuries, and health\u2010related quality of life"],"prefix":"10.1111","volume":"70","author":[{"given":"David A.","family":"Ganz","sequence":"first","affiliation":[{"name":"Department of Medicine David Geffen School of Medicine at UCLA  Los Angeles California USA"},{"name":"Geriatric Research Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita H.","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Medicine David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9473-830X","authenticated-orcid":false,"given":"Erich J.","family":"Greene","sequence":"additional","affiliation":[{"name":"Yale Center for Analytical Sciences, Department of Biostatistics Yale School of Public Health  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy K.","family":"Latham","sequence":"additional","affiliation":[{"name":"Boston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Araujo","sequence":"additional","affiliation":[{"name":"Yale Claude D. Pepper Older Americans Independence Center Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert L.","family":"Siu","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai  New York New York USA"},{"name":"Geriatric Research Education and Clinical Center, James J. 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