{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T05:04:44Z","timestamp":1777957484988,"version":"3.51.4"},"reference-count":55,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Canadian long\u2010term care facility (LTCF) residents experienced higher death rates compared to other countries during the first wave of the COVID\u201019 pandemic. This cohort study analyzes the individual, therapeutic, and institutional factors associated with death in LTCFs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Institutional data for 17 LTCFs in Montreal, Canada were obtained from local administrative registries. Individual data for 1197 residents infected by SARS\u2010CoV\u20102 between February 23 and July 11, 2020 were obtained through chart reviews. A multivariable modified Poisson regression model, which accounted for LTCF clustering, was used to identify resident and facility covariates associated with 30\u2010day mortality after COVID\u201019 diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Severe shortage of licensed practical nurses (RR 2.60 95% CI 1.20\u20135.61) and medium\u2010sized facilities compared to smaller\u2010sized facilities (RR 2.73 95% CI 1.23\u20136.07) were associated with 30\u2010day mortality. Later COVID\u201019 diagnosis (RR 0.98 95% CI 0.97\u20130.99 per additional day) was associated with survival. Individual risk factors for death included age (RR 1.33 95% CI 1.23\u20131.45 per additional 10\u2009years), male sex (RR 1.46 95% CI 1.24\u20131.71), functional impairment (RR 1.08 95% CI 1.04\u20131.12 per unit increase of SMAF), as well as a diagnosis of congestive heart failure (RR 1.31 95% CI 1.04\u20131.66) and neurocognitive disorder (RR 1.31 95% CI 1.01\u20131.70). Among severe cases, anticoagulation was associated with survival (RR 0.70 95% CI 0.51\u20130.96).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study identified practical nurse shortages and facility size as institutional risk factors for COVID\u201019 death. Anticoagulation was associated with survival among severe cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.17975","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T06:54:10Z","timestamp":1659164050000},"page":"3210-3220","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Institutional, therapeutic, and individual factors associated with\n                    <scp>30\u2010day<\/scp>\n                    mortality after\n                    <scp>COVID<\/scp>\n                    \u201019 diagnosis in Canadian long\u2010term care facilities"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3597-9987","authenticated-orcid":false,"given":"Xi Sophie","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of General Medicine CIUSSS Centre\u2010Sud\u2010de\u2010l'\u00cele\u2010de\u2010Montr\u00e9al  Montreal Canada"},{"name":"Department of Family and Emergency Medicine University of Montreal  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4879-2735","authenticated-orcid":false,"given":"Katia","family":"Charland","sequence":"additional","affiliation":[{"name":"Centre de recherche en sant\u00e9 publique  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1170-9475","authenticated-orcid":false,"given":"Caroline","family":"Quach","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Infectious Disease, and Immunology University of Montreal  Montreal Canada"},{"name":"Clinical Department of Laboratory Medicine Centre hospitalier universitaire de Sainte\u2010Justine (CHUSJ)  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5412-2597","authenticated-orcid":false,"given":"Quoc Dinh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CHUM)  Montreal Canada"},{"name":"Department of Medicine University of Montreal  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1388-1145","authenticated-orcid":false,"given":"Kate","family":"Zinszer","sequence":"additional","affiliation":[{"name":"Centre de recherche en sant\u00e9 publique  Montreal Canada"},{"name":"Department of Social and Preventive Medicine School of Public Health, University of Montreal  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2020.08.039"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD015085.pub2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2021.07.027"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010020\u201001954\u20105"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcaa343"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16669"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.13003"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0969733020939667"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520\u2010020\u201001784\u2010w"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10010008"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2020.104240"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2020.12.003"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16664"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41999\u2010020\u201000352\u20109"},{"issue":"7","key":"e_1_2_10_16_1","first-page":"303","article-title":"Age is not a disease: evolution of protective antibodies against SARS\u2010CoV\u20102 in seniors from the B\u0159evnice nursing home","volume":"159","author":"Fejt V","year":"2020","journal-title":"Cas Lek Cesk"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.4045\/tidsskr.20.0405"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2005412"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357\u2010021\u201000352\u2010y"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.17425"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2020.12.028"},{"key":"e_1_2_10_22_1","unstructured":"INSPQ. 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