{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:59:27Z","timestamp":1788602367196,"version":"build-2803163510"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K24 AG068312"],"award-info":[{"award-number":["K24 AG068312"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K76 AG06443"],"award-info":[{"award-number":["K76 AG06443"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P01 AG066605"],"award-info":[{"award-number":["P01 AG066605"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30 AG044281"],"award-info":[{"award-number":["P30 AG044281"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["T32 AG000212"],"award-info":[{"award-number":["T32 AG000212"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Older patients with poor prognosis cancers have complex needs that can benefit from geriatrics and palliative care principles. Because they are not routinely assessed, the prevalence of preexisting geriatric and palliative conditions in this population is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used the nationally representative Health and Retirement Study (HRS) linked with Medicare claims (1998\u20132016) to identify adults aged \u226565\u2009years diagnosed with poor prognosis cancers (cancers with a median survival \u22641\u00a0year). Using the HRS interview before the first Medicare cancer claim, we used survey\u2010weighted descriptive statistics and modified Poisson regression analysis to examine the prevalence of the following clinically significant conditions: functional impairment, difficulty with mobility, falls and injurious falls, social support, cognition, advance care planning, use of pain or sleep medications, and presence of pain or breathlessness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 2105 participants (mean age 76, 53% women, 34% lung cancer, 21% gastrointestinal cancer), the median survival was 9.6\u00a0months. Approximately 65% had difficulty climbing stairs (95% CI 63%\u201367%), 49% had no advance directive (95% CI 45%\u201354%), 35% lived alone (95% CI 33%\u201337%), 36% fell in the last 2\u2009years (95% CI 34%\u201338%), and 32% rated their memory as poor (95% CI 29%\u201334%). After adjusting for gender, cancer type, and HRS survey time before the first Medicare claim for a poor prognosis cancer, functional impairment and falls were highest among adults aged 85+. Adults aged 65\u201374\u2009years were less likely to have an advance directive. After adjusting for age, cancer type, and HRS survey time, women had a higher rate of pain and physical impairment. In exploratory analyses, race and socioeconomic status predicted difficulty with mobility and instrumental activities of daily living, living alone, and advance directive completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Due to a high prevalence across multiple domains, all older adults with poor prognosis cancers should be assessed for geriatric and palliative care conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.18039","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T05:01:14Z","timestamp":1666155674000},"page":"3402-3412","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The epidemiology of preexisting geriatric and palliative conditions in older adults with poor prognosis cancers"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1215-4210","authenticated-orcid":false,"given":"Mazie","family":"Tsang","sequence":"first","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Gan","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Medicine University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. John","family":"Boscardin","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Medicine University of California San Francisco  San Francisco California USA"},{"name":"Department of Epidemiology and Biostatistics University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6390-6959","authenticated-orcid":false,"given":"Melisa L.","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9642-6238","authenticated-orcid":false,"given":"Louise C.","family":"Walter","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Medicine University of California San Francisco  San Francisco California USA"},{"name":"Geriatrics, Palliative, and Extended Care Service Line San Francisco Veterans Affairs Medical Center  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-0861","authenticated-orcid":false,"given":"Alexander K.","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Medicine University of California San Francisco  San Francisco California USA"},{"name":"Geriatrics, Palliative, and Extended Care Service Line San Francisco Veterans Affairs Medical Center  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,19]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2016-0276"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.14950"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.34.7625"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2019.7355"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32658"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/OP.20.00442"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1353\/pbm.2017.0039"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.4158"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01789-X"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1000678"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.6676"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.1874"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2014.01.007"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu067"},{"issue":"2","key":"e_1_2_14_16_1","first-page":"170","article-title":"Proxy interviews and bias in the distribution of cognitive abilities due to non\u2010response in longitudinal studies: a comparison of HRS and ELSA","volume":"2","author":"Weir D","year":"2011","journal-title":"Longit Life Course Stud"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70259-0"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/nuf.12511"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0898264321991658"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.10.370"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2019.1665720"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh090"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afx166"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp239"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2013.11.009"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2015.0326"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2013.09.008"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/gby114"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03401.x"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/0733464818780631"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2009.06.006"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/59.1.S34"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glaa264"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2018.0338"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904-020-00556-7"},{"key":"e_1_2_14_36_1","article-title":"Why are we failing to do what works? Musings on outpatient palliative care integration in cancer care","volume":"18","author":"Kayastha N","year":"2021","journal-title":"JCO Oncol Pract"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.245803"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2020-143245"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15835"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.72.8170"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2019.08.011"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-017-0633-y"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15924"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2016.0113"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-010-1621-5"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000004"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.18039","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgs.18039","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.18039","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:00:54Z","timestamp":1762174854000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.18039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,19]]},"references-count":45,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/jgs.18039"],"URL":"https:\/\/doi.org\/10.1111\/jgs.18039","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,19]]},"assertion":[{"value":"2022-03-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}