{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:16:17Z","timestamp":1772169377250,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["5U01CE002955"],"award-info":[{"award-number":["5U01CE002955"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K08AG071794"],"award-info":[{"award-number":["K08AG071794"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We characterized real\u2010world prescribing patterns of opioids and benzodiazepines (BZDs) for older adults to explore potential disparities by race and sex and to characterize patterns of co\u2010prescribing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective evaluation was conducted using electronic health data for adults \u226565\u2009years old who presented to one of 15 primary care practices between 2019 and 2020 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a025,141). Chronic opioid and BZD users had \u22654 prescriptions in the year prior, with at least one in the last 90 or 180\u2009days, respectively. We compared demographic characteristics between all older adults versus chronic opioid and BZD users. We used logistic regression to identify characteristics (age, sex, race, Medicaid use, fall history) associated with opioid and BZD co\u2010prescribing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 833 (3.3%) chronic opioid and 959 chronic BZD users (3.8%) among all older adults seen in these practices. Chronic opioid users were less likely to be Black (12.7% vs. 14.3%) or other non\u2010White race (1.4% vs. 4.3%), but more likely to be women (66.8% vs. 61.3%). A similar trend was observed for BZD users, with less prescribing among Black (5.4% vs. 14.3%) and other races (2.2% vs. 4.3%) older adults and greater prescribing among women (73.6% vs. 61.3%). Co\u2010prescribing was observed among 15% of opioid users and 13% of BZD users. Co\u2010prescribing was largely driven by the presence of relevant co\u2010morbid conditions including chronic pain, anxiety, and insomnia rather than demographic characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We observed notable disparities in opioid and BZD prescribing by sex and race among older adults in primary care. Future research should explore if such patterns reflect appropriate prescribing or are due to disparities in prescribing driven by biases related to perceived risks for misuse.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.18288","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T07:58:45Z","timestamp":1676275125000},"page":"1944-1951","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Patterns and disparities in prescribing of opioids and benzodiazepines for older adults in North Carolina"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1466-5751","authenticated-orcid":false,"given":"Joshua D.","family":"Niznik","sequence":"first","affiliation":[{"name":"Division of Geriatric Medicine, Department of Medicine University of North Carolina at Chapel Hill, School of Medicine  Chapel Hill North Carolina USA"},{"name":"UNC Center for Aging and Health University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Division of Pharmaceutical Outcomes and Policy University of North Carolina at Chapel Hill, Eshelman School of Pharmacy  Chapel Hill North Carolina USA"},{"name":"Center for Health Equity Research and Promotion Veterans Affairs (VA) Pittsburgh Healthcare System  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamera","family":"Hughes","sequence":"additional","affiliation":[{"name":"Division of Practice Advancement and Clinical Education University of North Carolina at Chapel Hill, Eshelman School of Pharmacy  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4680-0156","authenticated-orcid":false,"given":"Lori T.","family":"Armistead","sequence":"additional","affiliation":[{"name":"Division of Practice Advancement and Clinical Education University of North Carolina at Chapel Hill, Eshelman School of Pharmacy  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayanth","family":"Kashyap","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Roller","sequence":"additional","affiliation":[{"name":"Division of Practice Advancement and Clinical Education University of North Carolina at Chapel Hill, Eshelman School of Pharmacy  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Busby\u2010Whitehead","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine, Department of Medicine University of North Carolina at Chapel Hill, School of Medicine  Chapel Hill North Carolina USA"},{"name":"UNC Center for Aging and Health University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie P.","family":"Ferreri","sequence":"additional","affiliation":[{"name":"Division of Practice Advancement and Clinical Education University of North Carolina at Chapel Hill, Eshelman School of Pharmacy  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201800321"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2018.02.011"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.7399"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.6721"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16911"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2020.07.036"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly283"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2018.24.9.875"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.00648"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1763"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.17764"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/2333721419878587"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-022-06164-5"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-014-0563-8"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa2034159"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2020.26.11.1468"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2006.00682.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2012\/15\/ES67"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2008.10.007"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-011-1770-9"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-021-02213-x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-006-0021-3"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1973.01750360007002"},{"key":"e_1_2_11_25_1","unstructured":"RadkeH.How a drug called Miltown ushered in an age of pill\u2010popping for anxious Americans. The Magic Bullet. 2018;(16). Published October 2018. Accessed May 20 2022.https:\/\/www.topic.com\/the-magic-bullet"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-200103000-00018"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.2217\/pmt.12.7"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.18288","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgs.18288","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.18288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T19:04:26Z","timestamp":1762196666000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.18288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,13]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/jgs.18288"],"URL":"https:\/\/doi.org\/10.1111\/jgs.18288","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,13]]},"assertion":[{"value":"2022-09-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}