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Serious falls were identified by Ecodes and a machine\u2010learning algorithm applied to radiology reports. Fragility fractures (hip, vertebral, and upper arm) were identified using ICD9 codes. Predictors for both models included a serious fall within the past 12\u2009months, body mass index, physiologic frailty (VACS Index 2.0), illicit substance and alcohol use disorders, and measures of multimorbidity and polypharmacy. We separately fit multivariable logistic models to each outcome using generalized estimating equations. From these models, the longitudinal extensions of average attributable fraction (LE\u2010AAF) for modifiable risk factors were estimated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Key risk factors for both outcomes included physiologic frailty (VACS Index 2.0) (serious falls [15%; 95% CI 14%\u201315%]; fractures [13%; 95% CI 12%\u201314%]), a serious fall in the past year (serious falls [7%; 95% CI 7%\u20137%]; fractures [5%; 95% CI 4%\u20135%]), polypharmacy (serious falls [5%; 95% CI 4%\u20135%]; fractures [5%; 95% CI 4%\u20135%]), an opioid prescription in the past month (serious falls [7%; 95% CI 6%\u20137%]; fractures [9%; 95% CI 8%\u20139%]), and diagnosis of alcohol use disorder (serious falls [4%; 95% CI 4%\u20135%]; fractures [8%; 95% CI 7%\u20138%]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study confirms the contributions of risk factors important in the general population to both serious falls and fragility fractures among older PWH. Successful prevention programs for these outcomes should build on existing prevention efforts while including risk factors specific to PWH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.18304","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T06:00:57Z","timestamp":1678687257000},"page":"1891-1901","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Assessing the contributions of modifiable risk factors to serious falls and fragility fractures among older persons living with\n                    <scp>HIV<\/scp>"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1003-0276","authenticated-orcid":false,"given":"Julie A.","family":"Womack","sequence":"first","affiliation":[{"name":"VA Connecticut Healthcare System  West Haven Connecticut USA"},{"name":"Yale School of Nursing  West Haven Connecticut 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