{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T07:18:44Z","timestamp":1779002324472,"version":"3.51.4"},"reference-count":51,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002489"],"award-info":[{"award-number":["UL1TR002489"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Multiple myeloma (MM) is an incurable debilitating blood cancer associated with the lowest health related quality of life (HRQoL) of all cancers. With nearly 88% of adults aged \u226555\u2009years at diagnosis, age\u2010associated physical losses, comorbidities, and social factors contribute to worsening HRQoL. This qualitative study assessed dyadic (patient\u2013informal caregiver) perspectives on the factors contributing to HRQoL in MM survivors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We recruited 21 dyads from the UNC\u2010Chapel Hill Lineberger Comprehensive Cancer between 11\/2021 and 04\/2022. Participants completed a single dyadic semistructured interview capturing broad perspectives on MM. We used ATLAS. ti v 9 for project management and to facilitate data analysis using the Sort and Sift, Think and Shift approach (ResearchTalk, Inc.). This iterative approach allowed the exploration and identification of themes within and across transcripts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age at enrollment was 71\u2009years (median: 71, range: 57\u201390) for patients and 68\u2009years (median 67, range: 37\u201388) for caregivers. All dyads were racially concordant (11 Black\/AA and 10 White). However, we aggregated the findings due to no consistent racial differences. Six themes related to (1) physical burden, (2) treatment challenges, (3) losses of independence, (4) caregiver burden, (5) patient and caregiver perseverance, and (6) adjustment to a new normal were identified. Dyads also experienced MM together, resulting in patients and caregivers experiencing changes in their ability to engage in physical and social activities, which further contributed to poor HRQoL. Patients' increased need for social support led to shifts in the caregiver roles, resulting in caregivers feeling burdened by their responsibilities. All dyads acknowledged the need for perseverance and adaptability to a new normal with MM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The functional, psychosocial, and HRQoL of older patients with MM and their caregivers remain impacted \u22656\u2009months after a new diagnosis highlighting clinical and research opportunities to focus on preserving or improving the health of dyads living with MM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.18482","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T09:48:35Z","timestamp":1686908915000},"page":"3208-3220","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["\u201cA lot to manage and still have some kind of a life\u201d: How multiple myeloma impacts the function and quality\u2010of\u2010life of Black\u2013White patient\u2013caregiver dyads"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1582-5593","authenticated-orcid":false,"given":"Lauren C.","family":"Bates\u2010Fraser","sequence":"first","affiliation":[{"name":"Department of Allied Health Sciences The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Lineberger Comprehensive Cancer Center The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiona","family":"Mills","sequence":"additional","affiliation":[{"name":"Gillings School of Global Public Health The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Mihas","sequence":"additional","affiliation":[{"name":"Odum Institute for Research in Social Sciences The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanya M.","family":"Wildes","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Hematology\/Oncology The University of Nebraska Medical Center\/Nebraska Medicine  Omaha Nebraska USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin E.","family":"Kent","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Gillings School of Global Public Health The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriell","family":"Erisnor","sequence":"additional","affiliation":[{"name":"School of Medicine City University of New York  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah","family":"Adams","sequence":"additional","affiliation":[{"name":"School of Medicine The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8481-3046","authenticated-orcid":false,"given":"Shakira J.","family":"Grant","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"School of Medicine The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Department of Medicine, Division of Hematology The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_13_3_1","unstructured":"SEER*Explorer: An Interactive Website for SEER Cancer Statistics[Internet]. 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