{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:36:30Z","timestamp":1781177790175,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K76AG074878"],"award-info":[{"award-number":["K76AG074878"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R24AG064025"],"award-info":[{"award-number":["R24AG064025"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Older adults are commonly prescribed long\u2010term benzodiazepines for anxiety and insomnia despite evidence of risks and limited evidence of long\u2010term benefits. Recent quality measures and guidelines have recommended benzodiazepine deprescribing, yet there is little real\u2010world data on clinic\u2010based deprescribing programs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We developed a benzodiazepine deprescribing quality improvement program for older adults at a large US academic medical center. The program targeted adults aged 65\u2009years and older who were prescribed chronic benzodiazepines by their primary care physician (PCP). PCPs were contacted to opt\u2010out patients not suitable for deprescribing; then eligible patients were mailed a letter discussing patient\u2010specific risks and advising them to discuss deprescribing with their PCP or a pharmacist who was available to support tapering. The primary outcomes were the number of patients who discussed deprescribing and who initiated a taper within 90\u2009days of outreach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 504 older adults prescribed benzodiazepines, 133 (26%) were opted out by their PCPs leaving a cohort of 371 (median age 71\u2009years [IQR 68\u201375], 58% female, 82% White). The median daily diazepam milligram equivalent was 5\u2009mg (IQR 3\u20136\u2009mg) and 30% were prescribed long\u2010acting benzodiazepines. Three months following patient outreach, 97 patients (26%) had a documented discussion of benzodiazepines with their PCP or clinic pharmacist. Of these patients, 35 (36%) had documentation of a deprescribing discussion and 25 (26%) initiated a taper. At 12\u2009months, 16 patients (64%) were tapered successfully, with nine (36%) patients taking a lower benzodiazepine dose and seven (28%) discontinuing benzodiazepines completely.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A low\u2010intensity benzodiazepine deprescribing outreach program led to deprescribing conversations for a minority of patients, but one\u2010quarter of older adults who engaged in a conversation chose to taper and nearly two\u2010thirds sustained reduced use. Incorporating benzodiazepine deprescribing into routine care may require more intensive population\u2010health efforts to engage patients and clinicians.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.18728","type":"journal-article","created":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T12:33:55Z","timestamp":1703594035000},"page":"1234-1241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Evaluation of a benzodiazepine deprescribing quality improvement initiative for older adults in primary care"],"prefix":"10.1111","volume":"72","author":[{"given":"Sulgi","family":"Chae","sequence":"first","affiliation":[{"name":"Department of Pharmacy Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Department of Psychiatry Kaiser Permanente  Santa Clara California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Healthcare Delivery Science Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Lindenberg","sequence":"additional","affiliation":[{"name":"Division of General Medicine Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaden","family":"Shen","sequence":"additional","affiliation":[{"name":"Northeastern University Bouve College of Health Sciences  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5384-275X","authenticated-orcid":false,"given":"Timothy S.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Center for Healthcare Delivery Science Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Division of General Medicine Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"},{"name":"Division of General Internal Medicine University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2016.303061"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03586.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16825"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15767"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12226"},{"key":"e_1_2_11_7_1","volume-title":"Deprescribing of Benzodiazepines in Older Adults","year":"2021"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-018-0544-4"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.15997"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-017-2257-8"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.16473"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-020-05886-z"},{"key":"e_1_2_11_13_1","article-title":"Evidence\u2010based clinical practice guideline for deprescribing benzodiazepine receptor agonists","volume":"64","author":"Pottie K","year":"2018","journal-title":"Can Fam Physician"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-022-07707-x"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.31490"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.japh.2022.09.025"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/17151635211014918"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.949"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.18728","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T17:25:18Z","timestamp":1762190718000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.18728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,26]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/jgs.18728"],"URL":"https:\/\/doi.org\/10.1111\/jgs.18728","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,26]]},"assertion":[{"value":"2023-08-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}