{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T22:12:47Z","timestamp":1766182367191,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:00:00Z","timestamp":1720483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K24AG080025","R01AG073321"],"award-info":[{"award-number":["K24AG080025","R01AG073321"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to examine the prevalence of inappropriate tight glycemic control in older adults with type 2 diabetes and other chronic conditions in New York City, and to identify factors associated with this practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study using the INSIGHT Clinical Research Network. The study population included 11,728 and 15,196 older adults in New York City (age\u2009\u2265\u200975\u2009years) with a diagnosis of type 2 diabetes, and at least one other chronic medical condition, in 2017 and 2022, respectively. The main outcome of interest was inappropriate tight glycemic control, defined as HbA1c &lt;7.0% (&lt;53\u2009mmol\/mol) with prescription of at least one high\u2010risk agent (insulin or insulin secretagogue).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The proportion of older adults with inappropriate tight glycemic control decreased by nearly 19% over a five\u2010year period (19.4% in 2017 to 15.8% in 2022). There was a significant decrease in insulin (27.8% in 2017; 24.3% in 2022) and sulfonylurea (29.4% in 2017; 21.7% in 2022) medication prescription, and increase in use of GLP\u20101 agonists (1.8% in 2017; 11.4% in 2022) and SGLT\u20102 inhibitors (5.8% in 2017; 25.1% in 2022), among the total population. Factors associated with inappropriate tight glycemic control in 2022 included history of heart failure (adjusted odds ratio [aOR] 1.38), chronic kidney disease ([aOR] 1.93), colorectal cancer ([aOR] 1.38), acute myocardial infarction ([aOR] 1.28), \u201cother\u201d ([aOR] 0.72) or \u201cunknown\u201d ([aOR] 0.72) race, and a point increase in BMI ([aOR] 0.98).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We found an encouraging trend toward less use of high\u2010risk medication strategies for older adults with type 2 diabetes and multiple chronic conditions. However, one in six patients in 2022 still had inappropriate tight glycemic control, indicating a need for continued efforts to optimize diabetes management in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.19060","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T11:53:13Z","timestamp":1720525993000},"page":"2721-2729","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Decline in use of high\u2010risk agents for tight glucose control among older adults with diabetes in New York City: 2017\u20132022"],"prefix":"10.1111","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7276-7962","authenticated-orcid":false,"given":"Jeff","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania","family":"Kanchi","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Conderino","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie K.","family":"Levy","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Clinical Innovation, Department of Medicine NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samrachana","family":"Adhikari","sequence":"additional","affiliation":[{"name":"Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saul","family":"Blecker","sequence":"additional","affiliation":[{"name":"Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nichola","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmin","family":"Divers","sequence":"additional","affiliation":[{"name":"Department of Foundations of Medicine NYU Grossman Long Island School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Rabin","sequence":"additional","affiliation":[{"name":"INSIGHT Clinical Research Network, Department of Population Health Sciences Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Weiner","sequence":"additional","affiliation":[{"name":"INSIGHT Clinical Research Network, Department of Population Health Sciences Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorna","family":"Thorpe","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Department of Population Health NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Dodson","sequence":"additional","affiliation":[{"name":"Division of Healthcare Delivery Science, Department of Population Health NYU Grossman School of Medicine  New York New York USA"},{"name":"Leon H. Charney Division of Cardiology, Department of Medicine NYU Grossman School of Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,9]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2015.10.004"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15335"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc\u20102020\u2010001585"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2012.0031"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S66821"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1003795"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f4533"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.6176"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12514"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc23\u2010S013"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.2007.s33"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.7345"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206286"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1911303"},{"key":"e_1_2_13_16_1","unstructured":"Our Data.2019Accessed August 21 2023.https:\/\/insightcrn.org\/our-data\/"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl\u20102014\u2010002764"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.5888\/pcd10.120137"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl\u20102011\u2010000116"},{"key":"e_1_2_13_20_1","unstructured":"New York City Department of Health and Mental Hygiene.Neighborhood poverty and infectious diseases: health disparities in New York City.20169."},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.12956"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.136"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)02074\u20108"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1603827"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18372"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k1497"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.19060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:13:15Z","timestamp":1762186395000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.19060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,9]]},"references-count":25,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/jgs.19060"],"URL":"https:\/\/doi.org\/10.1111\/jgs.19060","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"type":"print","value":"0002-8614"},{"type":"electronic","value":"1532-5415"}],"subject":[],"published":{"date-parts":[[2024,7,9]]},"assertion":[{"value":"2024-02-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}