{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:34:51Z","timestamp":1788914091352,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["NIDCDR21DC016359"],"award-info":[{"award-number":["NIDCDR21DC016359"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Falls pose a significant public health threat to older adults. Due to potential fall risk, guidelines recommend against the routine prescription of several medications commonly used for vestibular suppression, including meclizine and benzodiazepines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>We aimed to determine the factors associated with vestibular suppressant utilization among patients with dizziness \u2265\u200965\u2009years of age and subsequent falls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      A retrospective longitudinal database of US commercial insurance and Medicare beneficiaries was used to study medical claims data (January 1, 2006, through December 31, 2015). Of 190,348 individuals \u2265\u200965\u2009years old who presented with dizziness, 60,658 (32%) filled a vestibular suppressant prescription (27% anti\u2010emetics, 73% anxiolytics), of which 20,448 were women (34%) within a month after their dizziness diagnosis. Of those individuals using suppressants, 8% experienced a fall resulting in a medical encounter within 60\u2009days of filling the prescription. After adjusting for sociodemographics and comorbidity, individuals with dizziness who received vestibular suppressants were more likely to experience recorded fall incidents (hazard ratio (HR) 3.33, confidence interval (CI) 1.93\u20135.72,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), than those who did not receive vestibular suppressants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although vestibular suppressants may provide immediate relief from symptoms during an acute vestibular crisis, use is incongruent with guideline\u2010concordant care for most vestibular diagnoses and is also potentially counterproductive and injurious. Multi\u2010faceted interventions that engage clinicians and patients are needed to improve the value of care for patients with vestibular disorders to de\u2010implement the routine use of suppressants for dizziness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.19377","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T08:00:16Z","timestamp":1738656016000},"page":"1398-1405","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Vestibular Suppressant Utilization and Subsequent Falls Among Patients 65\u2009Years and Older With Dizziness in the United States"],"prefix":"10.1111","volume":"73","author":[{"given":"Schelomo","family":"Marmor","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of Minnesota  Minneapolis Minnesota USA"},{"name":"Department of Surgery University of Minnesota  Minneapolis Minnesota USA"},{"name":"Core for Clinical Quality Outcomes Discovery and Evaluation (CQODE) University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinar","family":"Karaca\u2010Mandic","sequence":"additional","affiliation":[{"name":"Department of Finance, Carlson School of Management University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith E.","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,4]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Center for Disease Control \u201cOnline resources \u201dhttps:\/\/www.cdc.gov\/falls\/data\/index.html."},{"key":"e_1_2_10_3_1","unstructured":"Center for Disease Control https:\/\/www.cdc.gov\/falls\/facts.html."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.48.5.488"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51452.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010019\u20101329\u20102"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/acem.14608"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459989210700117"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)05430-0"},{"key":"e_1_2_10_10_1","first-page":"878","article-title":"Effect of Drug Therapy on Compensation From Vestibular Injury","volume":"8","author":"Peppard S. B.","year":"1996","journal-title":"Laryngoscope"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-59989570317-9"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15767"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2017.08.042"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/01945998211004245"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2023.2840"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1742-6723.13810"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.315"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24806"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181f2f035"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2019.05.018"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/07317115.2018.1468377"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.08.022"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.1859"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2015.0500"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-2010-0530"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2022.1858"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.949"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102017\u2010015959"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816689667"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2022.0167"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/1077558716656970"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12770"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2022.05.012"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2005.02543.x"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.19377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T15:10:38Z","timestamp":1762182638000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.19377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,4]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/jgs.19377"],"URL":"https:\/\/doi.org\/10.1111\/jgs.19377","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,4]]},"assertion":[{"value":"2024-08-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}