{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:35:30Z","timestamp":1780464930443,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K23NS123340"],"award-info":[{"award-number":["K23NS123340"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["1R15AG070730\u201001A1"],"award-info":[{"award-number":["1R15AG070730\u201001A1"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"Division of Intramural Research","doi-asserted-by":"publisher","award":["1R38HL167282\u201001"],"award-info":[{"award-number":["1R38HL167282\u201001"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Higher physical activity (PA) is associated with better neuropsychiatric health, but prior studies have been limited by cross\u2010sectional designs, self\u2010reported PA measures, and small numbers of older individuals. We examined associations between baseline and changes in accelerometer\u2010measured moderate\u2010vigorous PA (MVPA) with neuropsychiatric health among individuals aged \u2265\u200970\u2009years in the National Health and Aging Trends Study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used the average daily minutes of accelerometer\u2010measured MVPA above a validated threshold of 2184 counts per minute as a continuous measure at baseline for the exposure variable. For longitudinal analyses, we categorized change in MVPA as follows: an increase of\u2009&gt;\u200920\u2009min\/day over 1\u2009year, a decrease of\u2009&gt;\u200920\u2009min\/day over 1\u2009year, and staying within 20\u2009min\/day over 1\u2009year. Our outcomes were possible\/probable dementia and anxiety or depression. Associations were estimated using confounder\u2010adjusted logistic regressions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In our survey\u2010weighted analytic sample of 639 individuals aged\u2009\u2265\u200970\u2009years, 56% were\u2009\u2265\u200975\u2009years, and 53% were female. After adjusting for confounders, a 20\u2010min\/day higher baseline MVPA was significantly associated with lower odds of possible\/probable dementia 1\u2009year later (odds ratio [OR]\u2009=\u20090.89, 95% confidence interval [CI]\u2009=\u20090.83\u20130.96) but not with depression and anxiety symptoms. Compared to no change in PA over 1\u2009year, an increase in MVPA by\u2009&gt;\u200920\u2009min\/day was associated with decreased odds of depression and anxiety symptoms (OR\u2009=\u20090.06, 95% CI\u2009=\u20090.03\u20130.14) but not with possible\/probable dementia. Compared to no change in MVPA over 1\u2009year, a decrease in MVPA by\u2009&gt;\u200920\u2009min\/day was associated with higher odds of possible\/probable dementia (OR\u2009=\u20093.82, 95% CI\u2009=\u20091.34\u201310.87) but not with depression and anxiety symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher and increasing MVPA over time is associated with better neuropsychiatric health in individuals aged \u2265\u200970\u2009years. Future studies should prioritize evaluating detailed PA trajectories to better understand how different doses, intensities, and modalities of PA impact neuropsychiatric decline in older adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.19383","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T07:18:05Z","timestamp":1738739885000},"page":"1870-1876","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Associations of Accelerometer\u2010Measured Physical Activity With Dementia, Anxiety, and Depression Among Older Adults"],"prefix":"10.1111","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-4597","authenticated-orcid":false,"given":"Eric L.","family":"Stulberg","sequence":"first","affiliation":[{"name":"Department of Neurology University of Pennsylvania  Philadelphia Pennsylvania USA"},{"name":"Department of Neurology University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0779-714X","authenticated-orcid":false,"given":"Lin\u2010Na","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy &amp; Athletic Training University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Gore","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Massachusetts General Hospital Institute of Health Professions  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly B.","family":"Conroy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J.","family":"Majersik","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4599-8543","authenticated-orcid":false,"given":"Katherine J.","family":"Hunzinger","sequence":"additional","affiliation":[{"name":"Department of Exercise Science Thomas Jefferson University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"LaPoint","sequence":"additional","affiliation":[{"name":"University of Utah School of Medicine  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandeep","family":"Kaur Sandhu","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy University of Texas Medical Branch  Galveston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea L. C.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Pennsylvania  Philadelphia Pennsylvania USA"},{"name":"Department of Biostatistics, Epidemiology, and Informatics University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0125-6759","authenticated-orcid":false,"given":"Amit","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy &amp; Athletic Training University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.65.10.1193"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(21)00140-9"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.12.1761"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e3181dba6d2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.35"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/08982643211029716"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2013.08.008"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.38526"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2021.113738"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-023-02644-z"},{"key":"e_1_2_8_12_1","unstructured":"J. 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