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Despite this, older adults remain underrepresented in GI clinical trials and research, limiting evidence\u2010based care. This review highlights three pivotal studies addressing this gap: (1) proton pump inhibitors, which are commonly used to treat gastroesophageal reflux disease, are not associated with the later development of dementia; (2) undertreatment of chronic inflammation among older adults with inflammatory bowel disease is associated with a higher rate of adverse events compared to treatment with anti\u2010TNF therapy, a biologic agent; (3) the majority (85%) of surveillance colonoscopies among older adults with a life expectancy of \u2265\u200910\u2009years did not yield colorectal cancer, advanced dysplasia, or \u2265\u20093 polyps.<\/jats:p>","DOI":"10.1111\/jgs.19467","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T09:08:01Z","timestamp":1744189681000},"page":"2338-2343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clin\u2010\n                    <scp>STAR<\/scp>\n                    Corner: Practice\u2010Changing Advances at the Interface of Gastroenterology &amp; 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