{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:57:06Z","timestamp":1791809826661,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["N01\u2010AG\u20106\u20102101"],"award-info":[{"award-number":["N01\u2010AG\u20106\u20102101"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["N01\u2010AG\u20106\u20102103"],"award-info":[{"award-number":["N01\u2010AG\u20106\u20102103"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["N01\u2010AG\u20106\u20102106"],"award-info":[{"award-number":["N01\u2010AG\u20106\u20102106"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01\u2010AG028050"],"award-info":[{"award-number":["R01\u2010AG028050"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["R01\u2010NR012459"],"award-info":[{"award-number":["R01\u2010NR012459"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["K23EY030897"],"award-info":[{"award-number":["K23EY030897"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000862","name":"Doris Duke Charitable Foundation","doi-asserted-by":"publisher","award":["2023\u20100232"],"award-info":[{"award-number":["2023\u20100232"]}],"id":[{"id":"10.13039\/100000862","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UM1TR004929"],"award-info":[{"award-number":["UM1TR004929"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Older adults with visual impairment (VI) have a greater risk of mortality, but the reasons are poorly understood. We have shown that older adults with VI are more likely to have poor mobility performance on the short physical performance battery (SPPB). In this analysis, we examined whether VI predicted mortality over 10\u2009years and if this was related to poor baseline mobility (SPPB &lt;\u20099).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed 2457 older adults (mean age 75.6 (\u00b12.8) years, 38.5% black, 51.9% female) who completed vision testing at the year 3 visit in the Health, Aging and Body Composition study. Cox proportional hazards models for mortality were right\u2010censored at 10\u2009years and adjusted for demographic and clinical comorbidities. VI (visual acuity &lt;\u200920\/40 or log contrast sensitivity &lt;\u20091.55 or stereoacuity &gt;\u200985) and SPPB &lt;\u20099 were tested as main predictors and their interaction was tested.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In separate multivariable models, VI (HR 1.511, 95% CI [1.335\u20131.709],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) and SPPB &lt;\u20099 (HR 1.442, 95% CI [1.210\u20131.717],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) each predicted mortality. When including both poor mobility and vision variables as main effects, both poor mobility and impaired vision remained significant predictors of mortality in all models (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). When adding poor mobility (as a main effect and interaction with VI) and using unimpaired vision and mobility as the reference, those with only VI (HR 1.467, 95% CI [1.287\u20131.672],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) or only poor mobility (HR 1.380, 95% CI [0.963\u20131.979],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0792) had similar HRs, while those with both VI and poor mobility had an increased mortality risk (HR 2.035, 95% CI [1.643\u20132.522],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), but the interaction was not significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.981).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Older adults with both VI and poor mobility are at an additive increased risk of mortality. Future interventions may want to target older adults with both VI and poor mobility to improve survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.19584","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T06:53:54Z","timestamp":1750229634000},"page":"3184-3189","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Relationship of Visual Impairment and Poor Mobility With Mortality"],"prefix":"10.1111","volume":"73","author":[{"given":"Atalie C.","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Surgical Ophthalmology Wake Forest University School of Medicine  Winston Salem North Carolina USA"},{"name":"Division of Gerontology and Geriatric Medicine Wake Forest University School of Medicine  Winston Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Rigdon","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science Wake Forest University School of Medicine  Winston Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Wake Forest University School of Medicine  Winston Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Kritchevsky","sequence":"additional","affiliation":[{"name":"Division of Gerontology and Geriatric Medicine Wake Forest University School of Medicine  Winston Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afw116"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2214\u2010109x(20)30549\u20100"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glac225"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1923"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gln022"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2023.10.010"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916\u2010016\u20100763\u20107"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2013.05.004"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2022.10.033"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1313.1990.tb01100.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gly244"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0886\u20103350(00)00562\u20109"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13183"},{"key":"e_1_2_10_15_1","first-page":"108","article-title":"The Frisby Stereo Test: Amended Instructions","volume":"37","author":"Frisby J.","year":"1980","journal-title":"British Orthoptic Journal"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/49.2.m85"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"issue":"8","key":"e_1_2_10_18_1","first-page":"314","article-title":"The Modified Mini\u2010Mental State (3MS) Examination","volume":"48","author":"Teng E. 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