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In this article, we review the prevalence of these conditions and the incidence of their complications. We recommend that physicians who provide primary and specialty care, as well as advanced practice practitioners (nurse practitioners and physician associates) who write prescriptions and orders for these treatments be incentivized to avoid these harms through carefully designed quality measures (QMs) and other strategies. We list several general and specific recommendations for strategies that we believe have the potential to reduce the incidence of iatrogenic hypoglycemia and iatrogenic hypotension and related complications in vulnerable older adults. Collaboration among health care organizations and facilities, health policy makers, professional organizations, individual health care providers, researchers, and patients will be essential in achieving this potential.<\/jats:p>","DOI":"10.1111\/jgs.70038","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T16:30:52Z","timestamp":1755102652000},"page":"6-14","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Strategies to Reduce Iatrogenic Hypoglycemia and Hypotension in Vulnerable Older Adults"],"prefix":"10.1111","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3985-5797","authenticated-orcid":false,"given":"Joseph G.","family":"Ouslander","sequence":"first","affiliation":[{"name":"Geriatric Medicine, Schmidt College of Medicine Florida Atlantic University  Boca Raton, Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wasserman","sequence":"additional","affiliation":[{"name":"California Association of Long\u2010Term Care Medicine  Santa Clarita, California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16395"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.19201"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1418"},{"key":"e_1_2_10_5_1","unstructured":"\u201cePrognosis \u201d accessed April 7 2025 https:\/\/eprognosis.ucsf.edu\/."},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15216"},{"key":"e_1_2_10_7_1","unstructured":"National Committee for Quality Assurance (NCQA) \u201cHEDIS Measures and Technical Resources \u201d accessed April 7 2025 https:\/\/www.ncqa.org\/hedis\/measures\/."},{"key":"e_1_2_10_8_1","unstructured":"National Committee for Quality Assurance \u201cImproving Care for Those With Advanced Illness and Frailty \u201d accessed April 7 2025 https:\/\/www.ncqa.org\/blog\/improving\u2010care\u2010advanced\u2010illness\u2010frailty\/."},{"key":"e_1_2_10_9_1","unstructured":"Blue Cross\/Blue Shield\/Blue Care Network \u201c2025 Star Measure Tips: HEDIS Advanced Illness and Frailty Guide \u201d accessed April 7 2025 www.bcbsm.com\/amslibs\/content\/dam\/public\/providers\/documents\/advanced\u2010illness\u2010frailty\u2010guide.pdf."},{"key":"e_1_2_10_10_1","unstructured":"D. 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