{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T02:31:33Z","timestamp":1771641093185,"version":"3.50.1"},"reference-count":59,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Underlying socio\u2010economic and health burden may variably impact delirium presentation among older adults. We characterized differences in patient factors related to social marginalization and studied their effects on delirium occurrence and hospital outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a 7\u2010year retrospective analysis of older adults (aged \u2265\u200970\u2009years) who systematically underwent screening for delirium at an 8\u2010hospital healthcare system. Our primary exposure included patient characteristics related to demographics and social marginalization. Multivariable logistic regression models were built to identify factors associated with increased odds of delirium occurrence, either (1) present\u2010on\u2010admission (D\u2010POA) or (2) hospital\u2010acquired (HAD). Secondary outcomes included hospital length of stay, in\u2010hospital mortality, and discharge disposition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 260,200 older adults were screened for delirium (median [IQR] age in years: 78.0 [74.0\u201384.0]; female: 143,402 [55.1%]; non\u2010Hispanic Black: 40,737 [15.8%]; Hispanic: 30,760 [11.9%]; median [IQR] Area Deprivation Index: 4.0 [2.0\u20136.0]; median [IQR] Charlson Comorbidity Index: 10.0 [8.0\u201313.0]). Rates of D\u2010POA were 25.5% across all screened patients. Among patients delirium\u2010free at admission, 10.4% later acquired HAD. In addition to known risk associations with older age and comorbidity burden, increased odds of D\u2010POA were observed for non\u2010Hispanic Black patients (aOR, 95% CI: 1.49, 1.44\u20131.54), Hispanic patients (aOR, 95% CI: 1.31, 1.26\u20131.36), higher ADI\u2010defined socio\u2010economic marginalization (aOR, 95% CI: 1.01, 1.00\u20131.01), and prior dementia (aOR: 6.53, 6.37\u20136.68). HAD risks were also higher for males (aOR, 95% CI: 1.07, 1.04\u20131.11), non\u2010Hispanic Black patients (1.39, 1.32\u20131.46), Hispanic patients (aOR, 95% CI: 1.28, 1.21\u20131.35), residence in higher ADI neighborhoods (aOR, 95% CI: 1.02, 1.02\u20131.03), and prior dementia (aOR, 95% CI: 2.44, 2.34\u20132.53). Effects of delirium on poor hospital outcomes did not differ by socio\u2010demographic sub\u2010groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Delirium risks were higher among minoritized and socio\u2010economically marginalized older adults. These findings present an opportunity to consider social marginalization as an important factor in delirium risk stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.70137","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T07:39:35Z","timestamp":1759217975000},"page":"3729-3737","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Social Disparities, Delirium Occurrence, and Related Outcomes Among Hospitalized Older Adults"],"prefix":"10.1111","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8782-8024","authenticated-orcid":false,"given":"Alan P.","family":"Pan","sequence":"first","affiliation":[{"name":"Center for Health Data Science and Analytics Houston Methodist  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist  Houston Texas USA"},{"name":"Department of Medicine Baylor College of Medicine  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Potter","sequence":"additional","affiliation":[{"name":"Center for Health Data Science and Analytics Houston Methodist  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Borei","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Houston Methodist  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Nowakowski","sequence":"additional","affiliation":[{"name":"Department of Medicine Baylor College of Medicine  Houston Texas USA"},{"name":"Houston Methodist Academic Institute Houston Methodist  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtenay R.","family":"Bruce","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist  Houston Texas USA"},{"name":"Houston Methodist Academic Institute Houston Methodist  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9795-2435","authenticated-orcid":false,"given":"George E.","family":"Taffet","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist  Houston Texas USA"},{"name":"Department of Medicine Baylor College of Medicine  Houston Texas USA"},{"name":"Houston Methodist Academic Institute Houston Methodist  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhaan S.","family":"Vahidy","sequence":"additional","affiliation":[{"name":"Houston Methodist Academic Institute Houston Methodist  Houston Texas USA"},{"name":"The Institute for Rehabilitation and Research Memorial Hermann Healthcare System  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h2538"},{"key":"e_1_2_9_3_1","first-page":"449","volume-title":"Handbook of Clinical Neurology","author":"Slooter A. 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