{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:35Z","timestamp":1787015555666,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30 AG028741"],"award-info":[{"award-number":["P30 AG028741"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2026,6]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n As the population ages, kidney transplantation (\n KT<\/jats:styled-content>\n ) is increasingly considered for older adults with advanced chronic kidney disease (\n CKD<\/jats:styled-content>\n ). However, frailty, cognitive impairment, and malnutrition complicate transplant decision\u2010making. A Comprehensive Geriatric Assessment (\n CGA<\/jats:styled-content>\n ) offers a multidimensional approach, but the relative contribution of individual\n CGA<\/jats:styled-content>\n domains to transplant eligibility and receipt remains unclear.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a retrospective observational study of 164 older adults with advanced\n CKD<\/jats:styled-content>\n seeking\n KT<\/jats:styled-content>\n and underwent\n CGA<\/jats:styled-content>\n by a geriatrician at an urban academic center from September 2021 to July 2024. Associations between\n CGA<\/jats:styled-content>\n domains and\n KT<\/jats:styled-content>\n listing and receipt were evaluated using logistic regression analyses, adjusting for age and other clinical covariates.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of the 164 participants, 139 (84.8%) were listed, and 24 (17.3%) received\n KT<\/jats:styled-content>\n among them. While higher levels of functional status, as measured by activities of daily living (\n ADL<\/jats:styled-content>\n ), were associated with\n KT<\/jats:styled-content>\n listing, instrumental\n ADL<\/jats:styled-content>\n and gait speed were significantly associated with transplantation. Even after adjusting for age, better cognitive function, as assessed through clinical evaluation and Montreal Cognitive Assessment (\n MoCA<\/jats:styled-content>\n ), was also positively associated with both outcomes. Age\u2010adjusted nutritional status was independently associated with transplant listing eligibility.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Individual domains of\n CGA<\/jats:styled-content>\n , particularly physical function, cognition, and nutrition, are independently associated with\n KT<\/jats:styled-content>\n decision\u2010making among older adults. Incorporating focused geriatric assessments into kidney transplant evaluation may improve risk stratification and reduce disparities in transplant access.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jgs.70324","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T16:28:47Z","timestamp":1769617727000},"page":"1558-1569","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Role of Geriatric Syndromes in Kidney Transplant Decision\u2010Making: A Domain\u2010Based Analysis of Comprehensive Geriatric Assessment in Older Adults"],"prefix":"10.1111","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3801-1472","authenticated-orcid":false,"given":"Ko","family":"Harada","sequence":"first","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihan","family":"Wang","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuka","family":"Shichijo","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared","family":"Doan","sequence":"additional","affiliation":[{"name":"Department of Graduate Medical Education Scripps Mercy Hospital San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Hung","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"Geriatric Research Education and Clinical Center James J Peters VA Medical Center Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Rosen","sequence":"additional","affiliation":[{"name":"Recanati\u2010Miller Transplantation Institute Mount Sinai Hospital New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"Baim\u2010Lance","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"Geriatric Research Education and Clinical Center James J Peters VA Medical Center Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Lerner","sequence":"additional","affiliation":[{"name":"Recanati\u2010Miller Transplantation Institute Mount Sinai Hospital New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olusegun","family":"Apoeso","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Ko","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"},{"name":"Geriatric Research Education and Clinical Center James J Peters VA Medical Center Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3488-2731","authenticated-orcid":false,"given":"Stephanie","family":"Chow","sequence":"additional","affiliation":[{"name":"Brookdale Department of Geriatrics and Palliative Medicine Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.1186\/s12882-025-04028-z","article-title":"The Global, Regional, and National Patterns of Change in the Burden of Chronic Kidney Disease From 1990 to 2021","volume":"26","author":"Guo J.","year":"2025","journal-title":"BMC Nephrology"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-025-21851-z","article-title":"Global, Regional, and National Burden of Chronic Kidney Disease and Its Underlying Etiologies From 1990 to 2021: A Systematic Analysis for the Global Burden of Disease Study 2021","volume":"25","author":"Deng L.","year":"2025","journal-title":"BMC Public Health"},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1053\/j.ajkd.2008.10.005","article-title":"United States Renal Data System 2008 Annual Data Report","volume":"53","author":"Collins A. 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