{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:42:17Z","timestamp":1792078937516,"version":"4.4.0"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["1R01AG061116"],"award-info":[{"award-number":["1R01AG061116"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Nonpharmacological strategies are first\u2010line treatments for behavioral symptoms, the most distressful aspect of dementia care. Few caregivers have knowledge of or access to effective strategies. We tested the effects of WeCareAdvisor, a web app to help caregivers problem\u2010solve and identify nonpharmacological strategies to manage behaviors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants\/Setting<\/jats:title>\n                    <jats:p>Two hundred and sixty\u2010two community\u2010living caregivers of people with dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Prospective two\u2010group randomized trial comparing immediate app users (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009131) to 3\u2010month delayed app users (controls,\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009131). Interviewers masked to participant allocation conducted baseline, 1\u2010(check\u2010in), and 3\u2010month (main endpoint) interviews. Using the DICE approach, immediate users answered brief questions to\n                      <jats:italic>describe<\/jats:italic>\n                      targeted behaviors and\n                      <jats:italic>investigate<\/jats:italic>\n                      contributors from which the app\n                      <jats:italic>creates<\/jats:italic>\n                      \u201cPrescriptions\u201d detailing strategies that caregivers\n                      <jats:italic>evaluate<\/jats:italic>\n                      if effective. Educational materials were also available. Three primary outcomes (caregiver distress, confidence managing behaviors, behavioral frequency by severity) and seven pre\u2010specified secondary (number, frequency, severity of behaviors, functional dependence and caregiver\u2010associated upset, wellbeing, and communications) outcomes were examined.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Caregivers were 63.8 (SD\u2009=\u200910.6) years old, mostly female (82%), spouses (65%), with some college (93%); 83% were White, 10% Black, 3% Asian, or other\/multi\u2010racial group (3.9%). Most (87%) lived with people with dementia who averaged 75.1 (SD\u2009=\u200910.5) years, were primarily male (57%) and White (82%), with moderate\u2013severe dementia (62%) and averaged 6.4 (SD\u2009=\u20092.8) behaviors. There were no treatment differences between groups in behavioral symptoms, or caregiver distress and confidence at 3\u2009months. However, the difference in caregiver distress between immediate versus delayed user groups was apparent over time by 3\u2009months (Bonferroni corrected\n                      <jats:italic>p<\/jats:italic>\n                      for interaction between time and intervention\u2009=\u20090.012). In secondary analyses, by 3\u2009months, immediate users versus controls, reported fewer behaviors (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02), less functional dependence (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.05) and associated caregiver upset (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005), and improved caregiver wellbeing (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>WeCareAdvisor use was associated with significant and clinically meaningful improvements in caregiver distress and wellbeing, although differences in frequency\/severity of behaviors were not significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      NCT05012410;\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT05012410\">https:\/\/clinicaltrials.gov\/study\/NCT05012410<\/jats:ext-link>\n                      . Initial registration date: 08\/12\/2021\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.70637","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:45:59Z","timestamp":1786038359000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of the\n                    <scp>WeCareAdvisor<\/scp>\n                    Web App on Behavioral Symptoms and Caregiver Outcomes: A Randomized Trial"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2869-473X","authenticated-orcid":false,"given":"Laura N.","family":"Gitlin","sequence":"first","affiliation":[{"name":"College of Nursing and Health Professions Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2465-6739","authenticated-orcid":false,"given":"Leslie A.","family":"McClure","sequence":"additional","affiliation":[{"name":"College for Public Health &amp; Social Justice Saint Louis University  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melinda J.","family":"Webster","sequence":"additional","affiliation":[{"name":"College of Nursing and Health Professions Drexel University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantine","family":"Lyketsos","sequence":"additional","affiliation":[{"name":"School of Medicine Johns Hopkins University  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen C.","family":"Kales","sequence":"additional","affiliation":[{"name":"University of California  Davis California 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