{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:00:48Z","timestamp":1790308848026,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R33AG071744"],"award-info":[{"award-number":["R33AG071744"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K24AG035075"],"award-info":[{"award-number":["K24AG035075"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AG030618"],"award-info":[{"award-number":["R01AG030618"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Since many hospitalized older adults have delirium, assessment of baseline cognitive function often requires proxy\u2010based measures. While the 16\u2010item Informant Questionnaire on Cognitive Decline in Elderly (IQCODE) specifies cutoff scores for mild cognitive impairment (MCI) and dementia, the 8\u2010item Informant Interview to Differentiate Aging and Dementia (AD8) provides only a single cutoff for \u201ccognitive impairment,\u201d limiting its usefulness and precision. Our aim was to develop a crosswalk between the IQCODE and AD8 to identify cutoff scores on the AD8 for MCI and dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The IQCODE and AD8 were administered to proxies of hospitalized older adults. We used two methods: equipercentile, which matches percentiles between IQCODE and AD8 score distributions, and item response theory (IRT), which matches estimated latent traits of the two measures, to create a crosswalk of equivalent scores and identify AD8 cutoff scores for MCI and dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 264 hospitalized older adults (mean age 79.5\u2009years, 55% women) and their proxies were recruited. Equipercentile and IRT methods yielded a crosswalk linking AD8 scores from 0 to 8 with IQCODE scores ranging from 1.0 to 5.0. An AD8 score of 2, corresponding to an IQCODE score of 3.2, was identified as the cutoff for MCI, while an AD8 score of 4, corresponding to an IQCODE score of 3.5, was identified as the cutoff for dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Our crosswalk equates AD8 and IQCODE scores and provides cutoff values for MCI and dementia for the AD8, enhancing its clinical utility in acute care. By establishing empirically derived thresholds, this study strengthens comparability across proxy\u2010based cognitive measures and expands the AD8's usefulness for distinguishing MCI from dementia. In acute settings, where delirium and time constraints limit direct testing, the AD8 offers a brief, reliable option for measuring baseline cognition and supporting early recognition of cognitive decline.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.70736","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:35:52Z","timestamp":1790307352000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Crosswalk of the\n                    <scp>IQCODE<\/scp>\n                    and\n                    <scp>AD8<\/scp>\n                    Proxy Dementia Screening Tools"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3817-747X","authenticated-orcid":false,"given":"Priyanka","family":"Shrestha","sequence":"first","affiliation":[{"name":"George Washington University, School of Nursing  Ashburn Virginia 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Brain Center Marcus Institute for Aging Research  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2911-4250","authenticated-orcid":false,"given":"Edward R.","family":"Marcantonio","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of General Medicine Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long H.","family":"Ngo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of General Medicine Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts 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