{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:51:57Z","timestamp":1791543117992,"version":"4.3.4"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["179845"],"award-info":[{"award-number":["179845"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Opioids and benzodiazepines (BZDs) are commonly prescribed for managing pain, anxiety, and sleep\u2010related problems following a hip fracture. Both opioids and BZDs carry risks of persistent dependence, falls, and mortality with long\u2010term use. Despite these risks, Canada lacks standardized prescribing guidelines for older adults with hip fracture. We examined population\u2010level trends in opioids and BZDs dispensing before hospitalization and up to 1\u2010year post\u2010discharge among older adults admitted for hip fractures in Ontario, Canada.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study using linked health administrative data from ICES, Ontario, Canada. The cohort included individuals aged 66\u2009years and older, residing in Ontario, admitted for an acute hip fracture between April 1, 2008, and March 31, 2024, and who survived for at least 275\u2009days in the following year. Our primary outcome was post\u2010discharge opioids and BZDs dispensed, defined as \u2265\u20091 prescription dispensed within 1\u2013365\u2009days following discharge. Secondary outcomes included pre\u2010hospitalization dispensing, concurrent dispensing, and morphine equivalent dose.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 114,055 eligible older adults were admitted with hip fractures between 2008 and 2024. Overall, BZDs dispensing declined from 33.7% in 2008 to 13.3% in 2024, while opioids dispensing peaked in 2015 at 55.8% and decreased to 44.6% in 2024. Hydromorphone and combination drug therapy were the most frequently dispensed opioid drug classes during pre\u2010hospitalization and post\u2010discharge periods following a hip fracture. Concurrent opioids and BZDs dispensed following a hip fracture decreased from 3.7% in 2008 to 1% in 2024. Among individuals with 90\u2009days of continuous opioid dispensed, most received &lt;\u200950\u2009mg average daily morphine equivalents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We observed a substantial reduction in BZDs dispensing. However, opioids dispensing remained consistently high. These findings underscore the need for future research on initiatives to reduce opioids use in post\u2010fracture care, while recognizing that opioids remain an effective pain control drug.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.70739","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:07:51Z","timestamp":1791540471000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Trends in Dispensing of Opioids and Benzodiazepines Among Older Adults Admitted for an Acute Hip Fracture Between 2008 and 2024 in Ontario, Canada"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1879-9917","authenticated-orcid":false,"given":"Anum","family":"Ali","sequence":"first","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1911-6129","authenticated-orcid":false,"given":"Mina","family":"Tadrous","sequence":"additional","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto  Toronto Ontario Canada"},{"name":"Women's College Hospital Research and Innovation Institute Women's College Hospital  Toronto Ontario Canada"},{"name":"ICES  Toronto Ontario Canada"},{"name":"Ontario Drug Policy Research Network  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5996-4543","authenticated-orcid":false,"given":"Chizaram","family":"Eje","sequence":"additional","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto  Toronto Ontario Canada"},{"name":"ICES  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2914-655X","authenticated-orcid":false,"given":"Laleh","family":"Rashidian","sequence":"additional","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto  Toronto Ontario Canada"},{"name":"Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9304-3039","authenticated-orcid":false,"given":"Arrani","family":"Senthinathan","sequence":"additional","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto  Toronto Ontario Canada"},{"name":"Holzschuh College of Business Administration, Niagara University  Lewiston New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4072-0083","authenticated-orcid":false,"given":"Cherry","family":"Chu","sequence":"additional","affiliation":[{"name":"Women's College Hospital Research and Innovation Institute Women's College Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6377-6653","authenticated-orcid":false,"given":"Kerry","family":"Kuluski","sequence":"additional","affiliation":[{"name":"Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health University of Toronto  Toronto Ontario Canada"},{"name":"Trillium Health Partners Mississauga, Institute for Better Health  Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9552-9139","authenticated-orcid":false,"given":"Sara J. T.","family":"Guilcher","sequence":"additional","affiliation":[{"name":"Leslie Dan Faculty of Pharmacy University of Toronto  Toronto Ontario Canada"},{"name":"ICES  Toronto Ontario Canada"},{"name":"St. John's Rehab Research Program Sunnybrook Research Institute  Toronto Ontario Canada"},{"name":"Department of Physical Therapy, Temerty Faculty of Medicine University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"issue":"3","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1046\/j.1532-5415.2003.51110.x","article-title":"Estimating Hip Fracture Morbidity, Mortality and Costs","volume":"51","author":"Braithwaite R. 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