{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:56:09Z","timestamp":1790776569321,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG062630"],"award-info":[{"award-number":["R01AG062630"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R33AG057806"],"award-info":[{"award-number":["R33AG057806"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["agsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J American Geriatrics Society"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Individuals with heart failure (HF) often have multiple complicating comorbidities. We examined whether cognitive and sensory (vision and hearing) impairments were independently associated with the risks of being hospitalized for HF or any cause in adults with HF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study among adults with HF from four US integrated healthcare delivery systems from 2005 to 2012. The presence of cognitive and sensory impairments were defined based on ICD\u20109 codes. We evaluated the association of cognitive and sensory impairments with hospitalization for HF and hospitalization for any cause using Fine\u2010Gray subdistribution hazard models, accounting for competing risks of death or health plan disenrollment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 43,358 eligible adults with HF, the mean age was 71.6\u2009years, 43% were women, 26% were racial\/ethnic minorities; 1104 had both cognitive and sensory impairments; 1079 had only cognitive impairment; 14,207 had only sensory impairment; and 26,968 had neither documented impairment at study entry. Individuals with both impairments had the lowest adherence to HF\u2010related medications as compared to those without impairments. After adjustment for several potential confounders and accounting for competing risk of death, compared to individuals without any documented impairment, those with only cognitive impairment and those with both impairments experienced a lower risk of HF\u2010related hospitalization (adjusted hazard ratio [aHR], 0.71 95% CI: 0.63\u20130.80) and (aHR 0.70 95% CI: 0.62\u20130.80), respectively. Similar trends were found for hospitalization for any cause.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In a diverse population of adults with HF, we observed a counterintuitive association between cognitive and sensory impairments and risks for hospitalization. Potential reasons include unmeasured confounders and receipt of care at home or through other non\u2010hospital facilities. More detailed studies are needed to fully delineate the impact of these impairments and to elucidate potential effective management strategies in this growing population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.70758","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:03:10Z","timestamp":1790773390000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Complex Relationship of Cognitive and Sensory Impairments With Risk of Hospitalization in Adults With Heart Failure"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8557-2029","authenticated-orcid":false,"given":"Mayra","family":"Tisminetzky","sequence":"first","affiliation":[{"name":"Division of Geriatric Medicine, Department of Medicine University of Massachusetts Chan Medical School  Worcester Massachusetts USA"},{"name":"Department of Population and Quantitative Health Sciences University of Massachusetts Chan Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Tabada","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California  Oakland California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1630-8213","authenticated-orcid":false,"given":"Jerry H.","family":"Gurwitz","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine, Department of Medicine University of Massachusetts Chan Medical School  Worcester Massachusetts USA"},{"name":"Department of Population and Quantitative Health Sciences University of Massachusetts Chan Medical School  Worcester Massachusetts USA"},{"name":"Division of Health Systems Science, Department of Medicine University of Massachusetts Chan Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristi","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of Research &amp; Evaluation Kaiser Permanente Southern California  Pasadena California USA"},{"name":"Department of Health Systems Science Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen P.","family":"Fortmann","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Center for Health Research Kaiser Permanente Northwest  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0735-0340","authenticated-orcid":false,"given":"Matthew T.","family":"Mefford","sequence":"additional","affiliation":[{"name":"Department of Research &amp; Evaluation Kaiser Permanente Southern California  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Research &amp; Evaluation Kaiser Permanente Southern California  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisha","family":"Garcia","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California  Oakland California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Madow","sequence":"additional","affiliation":[{"name":"Division of Health Systems Science, Department of Medicine University of Massachusetts Chan Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences University of Massachusetts Chan Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan S.","family":"Go","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California  Oakland California USA"},{"name":"Department of Health Systems Science Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"},{"name":"Kaiser Permanente Center for Health Research Kaiser Permanente Northwest  Portland Oregon USA"},{"name":"Department of Epidemiology, Biostatistics University of California, San Francisco  San Francisco California USA"},{"name":"Department of Medicine University of California, San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.246876"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/2235042X20940493"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.1317"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dad2.12054"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.11909\/j.issn.1671\u20105411.2014.04.007"},{"issue":"2","key":"e_1_2_11_7_1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1161\/CIRCOUTCOMES.108.801654","article-title":"The Cardiovascular Research Network: A New Paradigm for Cardiovascular Quality and Outcomes Research","volume":"1","author":"Go A. S.","year":"2008","journal-title":"Circulation. Cardiovascular Quality and Outcomes"},{"issue":"8","key":"e_1_2_11_8_1","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1586\/14779072.6.8.1043","article-title":"Creating a Research Data Network for Cardiovascular Disease: The CVRN","volume":"6","author":"Magid D. J.","year":"2008","journal-title":"Expert Review of Cardiovascular Therapy"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12062"},{"issue":"17","key":"e_1_2_11_10_1","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1001\/jama.296.17.2105","article-title":"Statin Therapy and Risks for Death and Hospitalization in Chronic Heart Failure","volume":"296","author":"Go A. S.","year":"2006","journal-title":"Journal of the American Medical Association"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000853"},{"issue":"3","key":"e_1_2_11_12_1","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1097\/MLR.0000000000000026","article-title":"Beyond Comorbidity: Expanding the Definition and Measurement of Complexity Among Older Adults Using Administrative Claims Data","volume":"52","author":"Chrischilles E.","year":"2014","journal-title":"Medical Care"},{"key":"e_1_2_11_13_1","unstructured":"U.S. Department of Health and Human Service \u201cMultiple Chronic Conditions\u2014A Strategic Framework: Optimum Health and Quality of Life for Individuals With Multiple Chronic Conditions \u201d(2010)."},{"issue":"1","key":"e_1_2_11_14_1","article-title":"The HMO Research Network Virtual Data Warehouse: A Public Data Model to Support Collaboration","volume":"2","author":"Ross T. R.","year":"2014","journal-title":"eGEMS (Washington, DC)"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/03610910902859574"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/00273171.2011.568786"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.5032\/jae.2011.01132"},{"key":"e_1_2_11_18_1","volume-title":"Designing and Conducting Survey Research: A Comprehensive Guide","author":"Rea L. M.","year":"2014"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2012.05.029"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0496"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.11.003"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-14-84"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.25522"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.m2021.0212"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15590"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14206"},{"issue":"9","key":"e_1_2_11_28_1","article-title":"Effectiveness of Transitional Care Interventions for Heart Failure Patients: A Systematic Review With Meta\u2010Analysis","volume":"14","author":"Al Sattouf A.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18266"}],"container-title":["Journal of the American Geriatrics Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.70758","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgs.70758","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgs.70758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:03:14Z","timestamp":1790773394000},"score":1,"resource":{"primary":{"URL":"https:\/\/agsjournals.onlinelibrary.wiley.com\/doi\/10.1111\/jgs.70758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":28,"alternative-id":["10.1111\/jgs.70758"],"URL":"https:\/\/doi.org\/10.1111\/jgs.70758","archive":["Portico"],"relation":{},"ISSN":["0002-8614","1532-5415"],"issn-type":[{"value":"0002-8614","type":"print"},{"value":"1532-5415","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"assertion":[{"value":"2026-06-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jgs.70758"}}