{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:44:49Z","timestamp":1788871489360,"version":"build-2803163510"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,10,21]],"date-time":"2013-10-21T00:00:00Z","timestamp":1382313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"European Union - cross-border cooperation programme"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Low adiponectin levels are discussed as risk factor for cardiovascular events. This is of special importance in individuals with type 2 diabetes (\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      ) because they are at higher risk for cardiovascular diseases. The present study aimed to investigate the effect of two plant oils rich in polyunsaturated fatty acids (\n                      <jats:styled-content style=\"fixed-case\">PUFA<\/jats:styled-content>\n                      ), with different content of omega\u20103 fatty acids, on adiponectin levels, glucose and lipid metabolism in\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      individuals treated either with insulin or oral anti\u2010diabetics (\n                      <jats:styled-content style=\"fixed-case\">OAD<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Ninety\u2010two subjects with\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      [34 treated with insulin (\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      \u2010Ins) and 58 treated with\n                      <jats:styled-content style=\"fixed-case\">OAD<\/jats:styled-content>\n                      (T2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">OAD<\/jats:styled-content>\n                      )] participated in this randomised, double\u2010blind, parallel intervention study. Individuals received either 9\u00a0g of nut oil (\n                      <jats:italic>n<\/jats:italic>\n                      \u20103:\n                      <jats:italic>n<\/jats:italic>\n                      \u20106 ratio: 1.3\u00a0:\u00a06.1) or mixed oil (\n                      <jats:italic>n<\/jats:italic>\n                      \u20103:\n                      <jats:italic>n<\/jats:italic>\n                      \u20106 ratio: 0.6\u00a0:\u00a05.7) per day for 10\u00a0weeks. The fatty acid profile, tocopherol, adiponectin levels and parameters regarding glucose and lipid metabolism were assessed at baseline, during and after the intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compliance was confirmed by significant increases in \u03b3\u2010tocopherol and\n                      <jats:styled-content style=\"fixed-case\">PUFA<\/jats:styled-content>\n                      in both oil groups. An increase in adiponectin levels in\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      \u2010Ins participants (+6.84% in nut oil and +4.47% in mixed oil group after 10\u00a0weeks compared to baseline) was observed, albeit not significantly different from\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">OAD<\/jats:styled-content>\n                      individuals (\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\n                      <jats:italic>\u00a0<\/jats:italic>\n                      0.051). Lipid and glucose metabolism were not affected by the intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The present study provides evidence that a small and easy change in dietary behaviour towards better fat quality moderately increases adiponectin levels in\n                      <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\n                      2\n                      <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n                      \u2010Ins subjects, independently of the administered plant oil.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.12168","type":"journal-article","created":{"date-parts":[[2013,10,21]],"date-time":"2013-10-21T06:50:37Z","timestamp":1382338237000},"page":"468-478","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Impact of polyunsaturated vegetable oils on adiponectin levels, glycaemia and blood lipids in individuals with type 2 diabetes: a randomised, double\u2010blind intervention study"],"prefix":"10.1111","volume":"27","author":[{"given":"E.","family":"M\u00fcllner","sequence":"first","affiliation":[{"name":"Department of Nutritional Sciences Emerging Field \u2018Oxidative Stress and DNA Stability' University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Plasser","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences Emerging Field \u2018Oxidative Stress and DNA Stability' University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Brath","sequence":"additional","affiliation":[{"name":"Diabetes Outpatient Clinic Health Centre South Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Waldsch\u00fctz","sequence":"additional","affiliation":[{"name":"Diabetes Outpatient Clinic Health Centre South Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Forster","sequence":"additional","affiliation":[{"name":"Diabetes Outpatient Clinic Health Centre South Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kundi","sequence":"additional","affiliation":[{"name":"Institute of Environmental Health Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.\u2010H.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences Emerging Field \u2018Oxidative Stress and DNA Stability' University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.3.585"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/74.1.72"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2011.01.001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90892.2008"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90288.2008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvr273"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60679-X"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-3597(09)60022-3"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2007.07.002"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn310"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00007379"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/65.5.1645S"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2006.10.009"},{"key":"e_1_2_7_15_1","first-page":"649","article-title":"Glucose tolerance and cardiovascular mortality","volume":"22","author":"Hu G.","year":"2001","journal-title":"Cardiovasc. 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