{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:24:26Z","timestamp":1740126266966,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T00:00:00Z","timestamp":1492387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI14\/00508"],"award-info":[{"award-number":["PI14\/00508"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Post\u2010prandial hypertriglyceridaemia (P\u2010<jats:styled-content style=\"fixed-case\">HTG<\/jats:styled-content>) is associated with cardiovascular disease. This association is of paramount importance during menopause, which is also related to reduced <jats:styled-content style=\"fixed-case\">high\u2010density lipoprotein<\/jats:styled-content>\u2010cholesterol (<jats:styled-content style=\"fixed-case\">HDL<\/jats:styled-content>c) and elevated triglyceride (<jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>) levels. We aimed to provide a self\u2010assesing tool to screen for P\u2010<jats:styled-content style=\"fixed-case\">HTG<\/jats:styled-content> in menopausal women who were normotriglyceridaemic at fasting and adhered to a Mediterranean\u2010style eating pattern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed oral fat loading tests (<jats:styled-content style=\"fixed-case\">OFLT<\/jats:styled-content>) in combination with self\u2010measurements of diurnal capillary <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>\u00a0at fixed time\u2010points (<jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content>) in 29 healthy menopausal women. <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content> levels &gt;220\u00a0mg\u00a0dL<jats:sup>\u22121<\/jats:sup> at any given time during the <jats:styled-content style=\"fixed-case\">OFLT<\/jats:styled-content> served as diagnostic criteria for P\u2010<jats:styled-content style=\"fixed-case\">HTG<\/jats:styled-content>. Subsequently, <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content> profiles were examined to determine the best mealtime (breakfast, lunch or dinner), as well as optimal cut\u2010off points to classify these women as having P\u2010<jats:styled-content style=\"fixed-case\">HTG<\/jats:styled-content> according to the <jats:styled-content style=\"fixed-case\">OFLT<\/jats:styled-content>. Insulin resistance was defined as the upper tertile of the homeostatic model assessment of insulin resistance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that, despite having normal fasting <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content> levels, P\u2010<jats:styled-content style=\"fixed-case\">HTG<\/jats:styled-content> was highly prevalent (approximately 40%). Moreover, self\u2010assessed 3\u2010h post\u2010lunch <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content> levels &gt;165\u00a0mg\u00a0dL<jats:sup>\u22121<\/jats:sup> increased the odds of having hypo\u2010<jats:styled-content style=\"fixed-case\">HDL<\/jats:styled-content> cholesterolaemia by 14.1\u2010fold (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.026) and the odds of having insulin resistance by 31.6\u2010fold (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.007), adjusted for total fat intake in women adhering to a Mediterranean eating pattern having their highest energy intake at lunch.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Self\u2010assessed 3\u2010h post\u2010lunch <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content> can be used to study post\u2010prandial <jats:styled-content style=\"fixed-case\">TG<\/jats:styled-content> metabolism in Southern European menopausal women who are normotriglyceridaemic at fasting. Characterising an individual's post\u2010prandial response may help menopausal women to evaluate their risk of cardiovascular disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jhn.12476","type":"journal-article","created":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T05:56:41Z","timestamp":1492408601000},"page":"700-708","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Post\u2010lunch triglyceridaemia associates with <scp>HDL<\/scp>c and insulin resistance in fasting normotriglyceridaemic menopausal women"],"prefix":"10.1111","volume":"30","author":[{"given":"A.","family":"Sanz\u2010Paris","sequence":"first","affiliation":[{"name":"Nutrition Department University Hospital Miguel Servet Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rodriguez\u2010Valle","sequence":"additional","affiliation":[{"name":"Clinical Biochemistry Department University Hospital Miguel Servet Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Navarro","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology University of Zaragoza Zaragoza Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Arag\u00f3n (IIS Arag\u00f3n) Zaragoza Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERObn) Instituto Salud Carlos III Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Puzo\u2010Foncillas","sequence":"additional","affiliation":[{"name":"Clinical Biochemistry Department University Hospital Miguel Servet Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8982-3737","authenticated-orcid":false,"given":"J. M.","family":"Arbones\u2010Mainar","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria Arag\u00f3n (IIS Arag\u00f3n) Zaragoza Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Fisiopatolog\u00eda Obesidad y Nutrici\u00f3n (CIBERObn) Instituto Salud Carlos III Madrid Spain"},{"name":"Adipocyte and Fat Biology Laboratory (AdipoFat) Translational Research Unit Instituto Aragon\u00e9s de Ciencias de la Salud (IACS) University Hospital Miguel Servet Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.3.299"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2010.02333.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.3.309"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-010-9501-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.19.11.2737"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(99)00315-9"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(00)00554-2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/ajcn\/74.2.171","article-title":"Effects of different nutrient intakes on daytime triacylglycerolemia in healthy, normolipemic, free\u2010living men","volume":"74","author":"Wijk JPH","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.2000.00732.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2003.07.006"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1006\/appe.1998.0191"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00280883"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2174\/157016111795495549"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.637793"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182160726"},{"key":"e_1_2_7_17_1","first-page":"1944","article-title":"Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cutpoints\u2010a joint consensus statement from the European atherosclerosis society and European federat","volume":"37","author":"Nordestgaard BG","year":"2016","journal-title":"Clin Chem"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(13)70191-8"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/67.1.31"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2174\/157016111795495530"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(98)00061-6"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/71.1.13"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096297"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980016001142"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2015.241752"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2013.12.013"}],"container-title":["Journal of Human Nutrition and Dietetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjhn.12476","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jhn.12476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T20:20:38Z","timestamp":1696018838000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jhn.12476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,17]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/jhn.12476"],"URL":"https:\/\/doi.org\/10.1111\/jhn.12476","archive":["Portico"],"relation":{},"ISSN":["0952-3871","1365-277X"],"issn-type":[{"type":"print","value":"0952-3871"},{"type":"electronic","value":"1365-277X"}],"subject":[],"published":{"date-parts":[[2017,4,17]]},"assertion":[{"value":"2017-04-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}