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The present study assessed whether a lifestyle intervention in breast cancer survivors could affect dietary biomarkers of fruit and vegetables and fatty acids.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this phase <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> single\u2010arm trial, 37 overweight\/obese early stage breast cancer patients completed a 12\u2010week diet and exercise intervention. The intervention involved 1\u2010h weekly diet sessions delivered by a dietician and 75\u2010min bi\u2010weekly physical activity sessions of moderate\u2010to\u2010high intensity led by trained monitors. Before and after the intervention, three 24\u2010h dietary recalls were carried out to calculate nutrient intakes and, in addition, blood samples were taken to measure plasma carotenoids, vitamin E and retinol concentrations and erythrocyte membrane fatty acid (<jats:styled-content style=\"fixed-case\">EFA<\/jats:styled-content>) composition. Wilcoxon signed rank tests were used to assess changes in dietary and biomarkers measurements over the intervention period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After the intervention, there was a significant increase in the intake of dietary carotenoids (+15.1% compared to baseline) but not plasma carotenoids levels (+6.3%). Regarding the <jats:styled-content style=\"fixed-case\">EFA<\/jats:styled-content> levels, we observed a significant decrease in percentage of saturated fatty acids (\u22121.4%) and <jats:italic>n<\/jats:italic>\u20106 polyunsaturated fatty acids (\u22122.9%) and an increase in monounsaturated fatty acids (1.7%) and total and long\u2010chain <jats:italic>n<\/jats:italic>\u20103 polyunsaturated fatty acids (by 13.1% and 13.7%, respectively). A favourable decrease in the ratio of long\u2010chain <jats:italic>n<\/jats:italic>\u20106 to <jats:italic>n<\/jats:italic>\u20103 polyunsaturated fatty acids (\u22129.1%) was also observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>After a short\u2010term diet and exercise intervention in overweight\/obese breast cancer survivors, we observed significant changes in dietary nutrients and fatty acid biomarkers, suggesting positive dietary changes that could be relevant for breast cancer prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jhn.12621","type":"journal-article","created":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T08:08:47Z","timestamp":1548058127000},"page":"468-479","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Changes in dietary intake, plasma carotenoids and erythrocyte membrane fatty acids in breast cancer survivors after a lifestyle intervention: results 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