{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T07:38:14Z","timestamp":1774078694968,"version":"3.50.1"},"reference-count":55,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T00:00:00Z","timestamp":1570752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["472021\/2011\u20107"],"award-info":[{"award-number":["472021\/2011\u20107"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vitamin A deficiency is still considered to be a nutritional problem during pregnancy, lactation and early childhood. The present study aimed to assess the vitamin A status of women and their newborns in the Brazilian Northeast and to determine the association between retinol in the maternal serum, umbilical cord blood and colostrum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Vitamin A status in 65 pairs of women and newborns was assessed from samples of the mother\u2019s serum, umbilical cord serum and colostrum using high\u2010performance liquid chromatography. The inadequacy of the vitamin A status of mothers and infants was identified if the retinol values were &lt;0.7\u00a0\u00b5mol\u00a0L<jats:sup>\u2212<\/jats:sup>1 in maternal serum or umbilical cord blood or &lt;1.05\u00a0\u00b5mol\u00a0L<jats:sup>\u22121<\/jats:sup> in colostrum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of inadequate maternal vitamin A status was 21.5% (95% CI: 11.5%\u201331.5%) and 13.8% [95% confidence interval (CI)\u00a0=\u00a05.4%\u201322.2%] based on maternal serum and colostrum, respectively. Among newborns, 41.5% (95% CI\u00a0=\u00a029.3%\u201353.5%) presented a low status of vitamin A based on cord serum. Multiple linear regression analysis identified that maternal serum retinol is a predictor of umbilical cord retinol (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005). Retinol in maternal serum was lower in mothers who were less educated (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04) and colostrum retinol was higher in older (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04) and multiparous (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.002) mothers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Vitamin A deficiency is a common problem among mothers attended in public hospitals in Northeast Brazil and maternal retinol concentrations are associated with retinol status in newborns. Maternal age, parity and educational level were related to the maternal vitamin A status.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jhn.12707","type":"journal-article","created":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T08:34:58Z","timestamp":1570782898000},"page":"222-231","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Retinol status and associated factors in mother\u2013newborn pairs"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2204-8622","authenticated-orcid":false,"given":"D.S.","family":"Bezerra","sequence":"first","affiliation":[{"name":"Department of Nutrition School of Health Sciences of Trairi\u00a0\u2013\u00a0Federal University of Rio Grande do Norte Santa Cruz Rio Grande do Norte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.D.S.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Nutrition\u00a0\u2013\u00a0Federal University of Rio Grande do Norte Natal Rio Grande do Norte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.S.R.","family":"Lima","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Bioscience Centre\u00a0\u2013\u00a0Federal University of Rio Grande do Norte Natal Rio Grande do Norte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.F.","family":"Pires Medeiros","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Bioscience Centre\u00a0\u2013\u00a0Federal University of Rio Grande do Norte Natal Rio Grande do Norte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.G.C.L.","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Nutrition\u00a0\u2013\u00a0Federal University of Rio Grande do Norte Natal Rio Grande do Norte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Dimenstein","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Bioscience Centre\u00a0\u2013\u00a0Federal University of Rio Grande do Norte Natal Rio Grande do Norte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.M.","family":"Os\u00f3rio","sequence":"additional","affiliation":[{"name":"Program in Nutrition\u00a0\u2013\u00a0Federal University of Pernambuco Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000342734"},{"key":"e_1_2_7_3_1","volume-title":"Global prevalence of vitamin A deficiency in populations at risk 1995\u20132005: WHO global database on vitamin A deficiency","author":"World Health Organization","year":"2009"},{"key":"e_1_2_7_4_1","unstructured":"Brasil(2009)Minist\u00e9rio da Sa\u00fade. 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