{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:20:17Z","timestamp":1768875617220,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T00:00:00Z","timestamp":1617926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The management of Prader\u2013Willi Syndrome (PWS) requires strict dietary supervision to prevent obesity, avoid micronutrient deficiencies and ensure optimal growth. The present study aimed to examine the growth and dietary intake of children with PWS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All children with genetically confirmed PWS attending Children's Health Ireland (CHI) at Tallaght (<jats:italic>n<\/jats:italic>\u00a0=\u00a044) were invited to participate. Anthropometry was performed and body composition measured using bioelectrical impedance analysis. Three\u2010day food diaries were used to evaluate dietary intake and the presence of early feeding issues was assessed. Serum haemoglobin, ferritin and vitamin D levels were measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen children participated, with a mean (range) age of 7.6\u00a0(0.6\u201318.1)\u00a0years. Most were female (<jats:italic>n<\/jats:italic>\u00a0=\u00a014, 74%). Twenty\u2010percent (<jats:italic>n<\/jats:italic>\u00a0=\u00a03) were underweight, 60% (<jats:italic>n<\/jats:italic>\u00a0=\u00a09) were healthy weight, <jats:italic>n<\/jats:italic>\u00a0=\u00a01 was overweight and <jats:italic>n<\/jats:italic>\u00a0=\u00a02 were obese. Mean (range) percentage body fat was 25.7% (10%\u201340%). Eigthy\u2010three percent reported early feeding issues. Ninety\u2010four percent (<jats:italic>n<\/jats:italic>\u00a0=\u00a016) achieved \u2264\u00a0100% of estimated average requirement (EAR) for energy. Mean daily energy intake for \u2264\u00a05\u00a0years old was 722\u00a0kcal (9\u00a0kcal\u00a0cm<jats:sup>\u20131<\/jats:sup>\/72\u2013112% EAR); for those \u2265\u00a012\u00a0years, it was 1203\u00a0kcal (8.3\u00a0kcal\u00a0cm<jats:sup>\u20131<\/jats:sup>\/41%\u201382% EAR). Suboptimal calcium, vitamin D, iron, zinc and fibre intake was evident. Iron deficiency anaemia and vitamin D insufficiency occurred in two children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study provides the first Irish data for PWS and shows that energy intake does not appear to be excessive, with four in five patients being underweight or of a normal BMI. Suboptimal dietary intake of several micronutrients was evident and biochemical nutrient deficiencies were present.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jhn.12882","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T13:00:22Z","timestamp":1617973222000},"page":"784-791","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Dietary intake and growth in children with Prader\u2013Willi syndrome"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6345-725X","authenticated-orcid":false,"given":"Christina","family":"Meade","sequence":"first","affiliation":[{"name":"Department of Nutrition and Dietetics Children\u2019s Health Ireland at Tallaght Tallaght University Hospital Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Martin","sequence":"additional","affiliation":[{"name":"Children\u2019s Health Ireland at Crumlin Cooley Road Crumlin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"McCrann","sequence":"additional","affiliation":[{"name":"Department of Paediatric Growth Diabetes and Endocrinology Children\u2019s Health Ireland at Tallaght Tallaght University Hospital Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Lyons","sequence":"additional","affiliation":[{"name":"Children\u2019s Health Ireland at Connolly Hospital Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edna","family":"Roche","sequence":"additional","affiliation":[{"name":"Discipline of Paediatrics Trinity College Dublin The University of Dublin Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.38.11.792"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201135"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2820"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33951"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2017-105118"},{"key":"e_1_2_12_7_1","first-page":"1993","volume-title":"Gene Reviews [Internet]","author":"Driscoll DJ","year":"2017"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23372"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-277X.2012.01275.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31507"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2011.09.010"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2009.105"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2018-0301"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2008.21.7.651"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118915349"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.73.1.25"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803232"},{"key":"e_1_2_12_18_1","unstructured":"Health Service Executive (HSE).Healthy Food for Life;2016.https:\/\/www.hse.ie\/eng\/about\/who\/healthwellbeing\/our\u2010priority\u2010programmes\/heal\/healthy\u2010eating\u2010guidelines. 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