{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:30:33Z","timestamp":1777365033092,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Iodine and animal protein may affect thyroid function. In the present study, we explored the association between animal protein intake and thyroid antibody status in pregnant women following universal salt iodisation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Pregnant women were enrolled using a multistage, stratified random sampling method in Shanghai. In total, 4646 eligible women were interviewed in person. We used a validated food frequency questionnaire and food composition tables to calculate the daily intakes of protein and iodine. We collected urine samples and performed thyroid antibody tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Positive thyrotropin receptor antibody (TR\u2010Ab) rates were different among animal protein intake groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Median urinary iodine concentration (UIC) was higher in the thyroid peroxidase antibody (TPO\u2010Ab) positive group than in the negative group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The median of total protein intake, animal protein intake and UIC was higher in the TR\u2010Ab positive group than in the negative group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The median of total protein intake and UIC was higher in the TPO\u2010Ab\/TG\u2010Ab\/TR\u2010Ab positive group than in the negative group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Multivariable logistic regression results showed that insufficient iodine had a negative correlation with positive TPO\u2010Ab and positive TR\u2010Ab (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The middle third and top third animal protein intakes served as protective factors for TR\u2010Ab (coefficient\u2009=\u20090.559, 95% confidence interval [CI]\u2009=\u20090.415\u20130.752,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; coefficient\u2009=\u20090.0.406, 95% CI\u2009=\u20090.266\u20130.621,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and positive TPO\u2010Ab\/TR\u2010Ab\/TG\u2010Ab (coefficient\u2009=\u20090.817, 95% CI\u2009=\u20090.687\u20130.971,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022; coefficient\u2009=\u20090.805, 95% CI\u2009=\u20090.672\u20130.964,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Adequate animal protein intake protects against elevated anti\u2010thyroid antibody levels in pregnant women with mild iodine deficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.12954","type":"journal-article","created":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T10:43:46Z","timestamp":1637405026000},"page":"542-553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of animal protein intake during pregnancy on autoimmune thyroiditis in pregnant women with mild iodine deficiency"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2170-7596","authenticated-orcid":false,"given":"Zhengyuan","family":"Wang","sequence":"first","affiliation":[{"name":"Division of Health Risk Factors Monitoring and Control Shanghai Municipal Center for Disease Control and Prevention Shanghai 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Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Su","sequence":"additional","affiliation":[{"name":"Division of Health Risk Factors Monitoring and Control Shanghai Municipal Center for Disease Control and Prevention Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajie","family":"Zang","sequence":"additional","affiliation":[{"name":"Division of Health Risk Factors Monitoring and Control Shanghai Municipal Center for Disease Control and Prevention Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03401381"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980015000464"},{"key":"e_1_2_11_4_1","first-page":"109","article-title":"Thyroid disorders in women","volume":"106","author":"Li 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